ChemBK
  • Home
  • Product Category

1-chloro-4-(trifluoromethyl)benzene

p-Chlorobenzotrifluoride

CAS: 98-56-6

Molecular Formula: C7H4ClF3

  1. Home
  2. Product Category
  3. Organic raw materials
  4. Organic fluoride
  5. 1-chloro-4-(trifluoromethyl)benzene

1-chloro-4-(trifluoromethyl)benzene - Names and Identifiers

Name p-Chlorobenzotrifluoride
Synonyms PCBTF
p-Chlorobenzotrifluoride
4-chlorobenzotrifluoride
P-chloro benzotrifluoride
For chlorobenzotrifluoride
4 chloro benzo trifluoride
para-Chlorobenzotrifluoride
p-chlorotrifluoromethylbenzene
4-chloro-α,α,α-trifluorotoluene
p-(trifluoromethyl)chlorobenzene
(p-chlorophenyl)trifluoromethane
1-chloro-4-(trifluoromethyl)-benzen
The three fluorine chlorine toluene
1-(Trifluoromethyl)-4-chlorobenzene
1-chloro-4-(trifluoromethyl)benzene
Benzene,1-chloro-4-(trifluoromethyl)-
4-Chloro-alpha,alpha,alpha-trifluorotoluene
alpha,alpha,alpha-trifluoro-4-chlorotoluene
para-chloro-alpha,alpha,alpha-trifluorotoluene
4,4,5,5,6,6,7,7,7-nonafluoro-2-hydroxyheptyl prop-2-enoate
CAS 98-56-6
EINECS 202-681-1
InChI InChI:1S/C7H4ClF3/c8-6-3-1-5(2-4-6)7(9,10)11/h1-4H
InChIKey QULYNCCPRWKEMF-UHFFFAOYSA-N

1-chloro-4-(trifluoromethyl)benzene - Physico-chemical Properties

Molecular FormulaC7H4ClF3
Molar Mass180.55
Density1.353 g/mL at 25 °C (lit.)
Melting Point-36 °C (lit.)
Boling Point136-138 °C (lit.)
Flash Point117°F
Water Solubility29 ppm (23 ºC)
Solubility 56mg/l
Vapor Presure10hPa at 25℃
AppearanceLiquid
Specific Gravity1.353
ColorClear colorless
Exposure LimitACGIH: TWA 2.5 mg/m3NIOSH: IDLH 250 mg/m3
Merck14,2126
BRN510203
Storage ConditionFlammables area
StabilityStable, but heat and light sensitive. Reacts vigorously with oxidizing agents. Flammable. Incompatible with sodium dimethyl sulfonate, strong bases.
Refractive Indexn20/D 1.446(lit.)
Physical and Chemical PropertiesThis product is liquid at normal temperature, m.p.-36 ℃, B. p.139.2 ℃,n20D 1.4460, relative density 1.353,f.p.117℉(47 ℃), soluble in benzene, toluene and other organic solvents.
UseFor pesticides, pharmaceuticals, dyes and other intermediates

1-chloro-4-(trifluoromethyl)benzene - Risk and Safety

Risk CodesR10 - Flammable
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S24/25 - Avoid contact with skin and eyes.
S16 - Keep away from sources of ignition.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDsUN 2234 3/PG 3
WGK Germany2
RTECSXS9145000
TSCAYes
HS Code29036990
Hazard NoteFlammable/Irritant
Hazard Class3
Packing GroupIII

1-chloro-4-(trifluoromethyl)benzene - Nature

Open Data Verified Data

colorless oily liquid. Melting Point -34 °c. Boiling point 139.3 °c. Relative density 1.334 (25 degrees C). Refractive index 4469(21 °c). Flash point 47 °c (closed Cup).

Last Update：2024-01-02 23:10:35

1-chloro-4-(trifluoromethyl)benzene - Preparation Method

Open Data Verified Data

The production methods of this product are liquid phase fluorination of chloromethyl benzene and catalytic method, which mainly uses the liquid phase fluorination of chloromethyl benzene, that is, the chlorine trichloromethyl benzene in the catalyst and pressure (can also be atmospheric pressure) fluorination was carried out at low temperature (<100 °c) with anhydrous hydrogen fluoride.

Last Update：2022-01-01 10:41:22

1-chloro-4-(trifluoromethyl)benzene - Use

Open Data Verified Data

This product is used as trifluralin, ethidine trifluralin, fluoroester oxime grass ether, fluoroiodoamine grass ether, and carboxyfluoroether herbicide, etc. It can also be used in synthetic medicine, in addition, it can also be used in the dye industry.

Last Update：2022-01-01 10:41:21

1-chloro-4-(trifluoromethyl)benzene - Safety

Open Data Verified Data
  • toxic. Inhalation can be toxic and irritating. In case of high temperature, open flame, oxidant has caused the risk of combustion.
  • This product is irritating, with galvanized iron barrel, each net weight 200kg, stored in the ventilation sunscreen, moisture-proof place.
Last Update：2022-01-01 10:41:22

1-chloro-4-(trifluoromethyl)benzene - Reference Information

LogP3.7 at 25℃
(IARC) carcinogen classification 2B (Vol. 125)
NIST chemical information information provided by: webbook.nist.gov (external link)
EPA chemical substance information information provided by: ofmpeb.epa.gov (external link)
Introduction 4-chloro trifluorotoluoride (4-chloro benzotrifluoride) is a colorless transparent liquid with a halogenated benzene odor. The compound is insoluble in water and miscible with benzene, toluene, ethanol, diethyl ether, halogenated hydrocarbons, etc.
Application p-chlorotrifluorotoluene is an important intermediate in organic synthesis, containing fluorine atoms to give it special activity, in medicine, pesticides, dyes and other fields of fine organic synthesis are widely used. P-chlorotrifluorotoluene is a key intermediate for the synthesis of a variety of fluorine-containing insecticides and herbicides on pesticides. At present, the most used are the synthesis of trifluralin, ethidine trifluoromethyl, fluorine Ester oxime ether, fluorine iodoamine grass ether, as well as the carboxyl fluoride ether herbicide, etc.
uses p-chlorotrifluorotoluene is the herbicide trifluralin, ethoxyfluoroxane, the intermediates of milk fluorine and grass spirit, etc.
This product is used as trifluralin, ethidine trifluralin, fluoroester oxime grass ether, fluoroiodoamine grass ether, and carboxyfluoroether herbicide, etc. It can also be used in synthetic medicine, in addition, it can also be used in the dye industry.
used as pesticide, medicine, dye and other intermediates
production method p-chlorotoluene is obtained by side chain light chlorination and liquid phase fluorination: chlorination: P-chlorotoluene was put into a photo-chlorination reactor, heated to 120-150 ° C., and subjected to chlorine reaction under the irradiation of a fluorescent lamp. The reaction solution was analyzed by gas chromatography every 10-15min. The reaction was stopped when the p-chlorotoluene content was more than 90%. The product was distilled under reduced pressure to obtain p-chloro-trichlorotoluene. The yield was 90-95%. Fluorination: P-chloro-trichlorotoluene was put into a fluorination reaction kettle, and 4-5 times of anhydrous hydrogen fluoride was added in a molar ratio. After raising the temperature, the reaction was carried out at 1.9-2.4MPa until the reaction pressure did not rise any more. The hydrogen chloride gas released in the reaction process is absorbed by alkali, and the reactant is neutralized and distilled by steam to obtain a crude product. The p-chlorotrifluorotoluene liquid with a boiling range of 138-140 ° C. Is obtained by frequent pressure distillation. The yield was 80-90%.
The preparation method is to add P-chlorotrichlorotoluene to the fluorination reactor, cool the condenser with chilled brine, press the metered liquid hydrogen fluoride from the cylinder with dry air to the fluorination reactor, and then add the catalyst, the control valve is closed, and the reaction is stirred and heated. The hydrogen fluoride produced by the reaction is condensed and refluxed with volatile hydrogen fluoride and organic matter, and the condensed and recovered liquid hydrogen fluoride is stored in the recovery tank. After the reaction is finished, the fluorinated product P-chlorotrifluorotoluene enters the distillation kettle, the product is obtained by heating and distillation under vacuum system.
category flammable liquid
toxicity grade low toxicity
Acute toxicity oral-rat LD50: 13000 mg/kg; Oral-mouse LD50: 11500 mg/kg
explosive hazard characteristics reacts with sodium dimethyl sulfinate to release a large amount of heat, explosive
flammability hazard characteristics open flame flammable; Thermal decomposition of toxic halide gases
storage and transportation characteristics The warehouse is ventilated and dried at low temperature; Storage and transportation are separated from oxidant and food raw materials
fire extinguishing agent carbon dioxide, sand, foam
toxic substance data information provided by: pubchem.ncbi.nlm.nih.gov (external link)
Last Update：2024-04-09 20:02:46
1-chloro-4-(trifluoromethyl)benzene
Supplier List
JIANGSU BSECHEM CHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: p-Chlorobenzotrifluoride Request for quotation
CAS: 98-56-6
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685 Click to send a QQ messageSend QQ message
Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: p-Chlorobenzotrifluoride Request for quotation
CAS: 98-56-6
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: p-Chlorobenzotrifluoride Request for quotation
CAS: 98-56-6
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
Spot supply
Product Name: Sorafenib Impurity 116 Visit Supplier Webpage Request for quotation
CAS: 98-56-6
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: p-Chlorobenzotrifluoride Request for quotation
CAS: 98-56-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Shanghai Worldyang Chemical Co.,Ltd.
Product Name: p-Chlorobenzotrifluoride Request for quotation
CAS: 98-56-6
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228 Click to send a QQ message
Wechat: 13651600618
WhatsApp: +8613651600618
JIANGSU BSECHEM CHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: p-Chlorobenzotrifluoride Request for quotation
CAS: 98-56-6
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685 Click to send a QQ messageSend QQ message
Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: p-Chlorobenzotrifluoride Request for quotation
CAS: 98-56-6
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: p-Chlorobenzotrifluoride Request for quotation
CAS: 98-56-6
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
Spot supply
Product Name: Sorafenib Impurity 116 Visit Supplier Webpage Request for quotation
CAS: 98-56-6
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: p-Chlorobenzotrifluoride Request for quotation
CAS: 98-56-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Shanghai Worldyang Chemical Co.,Ltd.
Product Name: p-Chlorobenzotrifluoride Request for quotation
CAS: 98-56-6
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228 Click to send a QQ message
Wechat: 13651600618
WhatsApp: +8613651600618
View History
1-chloro-4-(trifluoromethyl)benzene
  • Home
  • Product Category

© 2015, 2023 ChemBK.com All Rights Reserved | Build: 20230617001