1-phenylpiperazine hydrochloride

1-phenylpiperazine hydrochloride - Names and Identifiers

Name	1-phenylpiperazinium chloride
Synonyms	TIMTEC-BB SBB003556 PHENYL PIPERAZINE HCL 1-PHENYLPIPERAZINE HCL 1-phenylpiperazinium chloride 1-phenyl-piperazinhydrochloride 1-phenylpiperazine hydrochloride 1-PHENYLPIPERAZINE HYDROCHLORIDE N-PHENYLPIPERAZINE HYDROCHLORIDE 1-PHENYLPIPERAZINE MONOHYDROCHLORIDE
CAS	2210-93-7
EINECS	218-646-9
InChI	InChI=1/C10H14N2.ClH/c1-2-4-10(5-3-1)12-8-6-11-7-9-12;/h1-5,11H,6-9H2;1H

1-phenylpiperazine hydrochloride - Physico-chemical Properties

Molecular Formula	C10H15ClN2
Molar Mass	198.69
Density	0.985(20.0000℃)
Melting Point	247-250°C(lit.)
Boling Point	287.2°C at 760 mmHg
Flash Point	138.3°C
Vapor Presure	0.00252mmHg at 25°C
Storage Condition	Room Temprature
MDL	MFCD00012758

1-phenylpiperazine hydrochloride - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S28 - After contact with skin, wash immediately with plenty of soap-suds. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	TM2640000
HS Code	29335990
Hazard Class	6.1
Packing Group	III

1-phenylpiperazine hydrochloride - Introduction

1-phenylpiperazinium chloride is an organic compound with the chemical structural formula C11H15ClN2. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
1-phenylpiperazinium chloride is a solid, usually white crystalline or crystalline powder. It has high solubility in water and can be dissolved into a colorless and transparent solution. The compound is stable at room temperature and is not easily decomposed by volatilization.

Use:
1-phenylpiperazinium chloride has certain application value in the field of medicine. It is used as a pharmaceutical intermediate for the preparation of some antipsychotic drugs, sedative drugs and antidepressant drugs.

Method:
A common method for preparing 1-phenylpiperazinium chloride is through the synthesis of piperazine compounds followed by Arylation. The specific steps are as follows:
1. Piperazine and phenyl reagent (such as bromobenzene, fluorobenzene, etc.) reaction, the corresponding substituted piperazine compounds.
2. The substituted piperazine compound is reacted with hydrochloric acid to generate 1-phenylpiperazinium chloride.
3. Purify and crystallize to obtain pure 1-phenylpiperazinium chloride.

Safety Information:
Although there is no clear safety data report to provide information on 1-phenylpiperazinium chloride, as an organic compound, safety measures should be taken to use it. Direct contact with the compound may cause irritation and inhalation or ingestion should be avoided. Wear appropriate protective equipment during operation and avoid contact with skin, eyes and respiratory tract. Properly store and avoid mixing with oxidants, acids, alkalis and other substances. When using and handling, please follow the laboratory's safe operating procedures. When handling any chemical substance, be sure to refer to and comply with the safety data sheet for that substance.

Last Update：2024-04-09 20:15:17