1-乙基-6,7,8-三氟-1,4-二氢-4-氧代-3-喹啉甲酸乙酯

1-乙基-6,7,8-三氟-1,4-二氢-4-氧代-3-喹啉甲酸乙酯 - Names and Identifiers

Name	Ethyl 1-ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate
Synonyms	ethyl 1-ethyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate Ethyl 1-ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate ethyl 1-ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate 1-Ethyl-6,7,8-trifluoro-4-oxohydroquinone-3-carboxylic acid ethyl ester ETHYL-6,7,8-TRIFLUORO-N-ETHYL-2,5-THIHYDRO-4-OXO-3-QUINOLINE CARBOXYLATE 1-Ethyl-6,7,8-Trifluoro-4-Oxohydroquinoline-3-carboxylic Acid Ethyl Ester 1-Ethyl-6,7,8-trifluoro-4-oxohydroquinoline-3-carboxylic acid ethyl ester 1-ETHYL-6,7,8-TRIFLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACID ETHYL ESTER 1-Ethyl-6,7,8-Trifluoro-1,4-Dihydro-4-Fluoroquiroline-3-Carboxylic Acid Ethyl Ester 1-ETHYL-6,7,8-TRIFLUORO-1,4-DIHYDRO-4-FLUOROQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 1-Ethyl-6,7,8-trifluoro-1,4-dihydro -4-oxohydroquinoline-3-carboxylic acid ethyl ester
CAS	100501-62-0
EINECS	405-880-3
InChI	InChI=1/C14H12F3NO3/c1-3-18-6-8(14(20)21-4-2)13(19)7-5-9(15)10(16)11(17)12(7)18/h5-6H,3-4H2,1-2H3

1-乙基-6,7,8-三氟-1,4-二氢-4-氧代-3-喹啉甲酸乙酯 - Physico-chemical Properties

Molecular Formula	C14H12F3NO3
Molar Mass	299.25
Density	1.363±0.06 g/cm3(Predicted)
Melting Point	204-208 °C
Boling Point	392.3±42.0 °C(Predicted)
Flash Point	191°C
Vapor Presure	2.32E-06mmHg at 25°C
Appearance	White powder
pKa	0.18±0.70(Predicted)
Storage Condition	2-8℃
Refractive Index	1.519
MDL	MFCD00276022
Physical and Chemical Properties	Melting Point 204-208°C

1-乙基-6,7,8-三氟-1,4-二氢-4-氧代-3-喹啉甲酸乙酯 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R43 - May cause sensitization by skin contact R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Description	S24 - Avoid contact with skin. S37 - Wear suitable gloves. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
WGK Germany	2

1-乙基-6,7,8-三氟-1,4-二氢-4-氧代-3-喹啉甲酸乙酯 - Introduction

1-Ethyl-6, 7,8-trifluoro-1, 4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester is an organic compound with the chemical formula C12H13F3NO3.

Its properties are as follows:
-Appearance is colorless liquid
-May have pungent odor
-Molecular weight of 283.23g/mol
-Melting point is approximately -30°C
-Boiling point is about 220°C
-May be insoluble in water
-May be miscible with some organic solvents

The main uses of 1-ethyl-6, 7,8-trifluoro-1, 4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester include:
-As a pesticide intermediate: It can be used to synthesize some pesticides, such as ethyl metamidiphosphate.
-As an intermediate in organic synthesis: It can be used to synthesize some organic compounds, such as ester compounds.

The preparation of 1-ethyl -6,7,8-trifluoro -1,4-dihydro -4-oxo -3-quinoline carboxylic acid ethyl ester usually adopts chemical synthesis method. The specific preparation method may include the following steps:
1. Add 1-ethyl-3-amino-4-oxo-6, 7,8-trifluoro-1, 4-dihydroquinoline carboxylic acid ethyl ester and acidic solvent to the reaction vessel.
2. Under low temperature conditions, the acidic esterifying agent is gradually added to the reaction vessel.
3. After the reaction is completed, the target product is extracted and purified by distillation and other means.

Regarding safety information, 1-ethyl-6, 7,8-trifluoro-1, 4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester is an organic compound and has certain safety risks. Here are some suggestions:
-Wear appropriate personal protective equipment such as chemical goggles and protective gloves during use.
-Avoid contact with skin, eyes and mucous membranes, rinse immediately with plenty of water and seek medical help.
-Avoid inhaling the vapor or mist of the substance, and operate in a well-ventilated place.
-Pay attention to avoid fire and high temperature during use and storage.

Please note that the information provided above is for reference only. For specific experiments or applications, please be sure to refer to the exact laboratory operating methods and safety materials.

Last Update：2024-04-10 22:29:15