1001907-23-8

1001907-23-8 - Names and Identifiers

Name	tert-butyl 5-iodo-1H-indazole-1-carboxylate
Synonyms	ert-butyl5-iodoindazole-1-carboxylate tert-butyl 5-iodoindazole-1-carboxylate tert-butyl 5-iodo-1H-indazol-1-carboxylate tert-butyl 5-iodo-1H-indazole-1-carboxylate 5-Iodo-indazole-1-carboxylic acid tert-butyl ester 1H-Indazole-1-carboxylic acid, 5-iodo-, 1,1-diMethylethyl ester
CAS	1001907-23-8

1001907-23-8 - Physico-chemical Properties

Molecular Formula	C12H13IN2O2
Molar Mass	344.15
Storage Condition	Room Temprature

1001907-23-8 - Introduction

N-Boc-5-iodoindazole is an organic compound whose chemical name is N-tert-butoxycarbonyl-5-iodoindazole. The following is a description of its nature, use, formulation and safety information:

Nature:
N-Boc-5-iodoindazole is a solid compound with a molecular formula of C11H12IN3O2 and a relative molecular mass of 337.14g/mol. It has a white or pale yellow crystalline form and can be dissolved in an organic solvent such as methylene chloride or ether. Its melting point is about 82-83°C. N-Boc-5-iodoindazole is a reagent grade compound commonly used as a reagent in organic synthesis.

Use:
N-Boc-5-iodoindazole is commonly used as an intermediate in pharmaceutical synthesis and organic synthesis. It can be used as a protecting group for 5-iodoindazole to protect the active site of indazole for subsequent chemical reactions. In addition, N-Boc-5-iodoindazoles can also be used in the synthesis of other organic compounds, such as pyrazoles or indoles.

Preparation Method:
N-Boc-5-iodoindazole is generally prepared by reacting N-Boc-5-chloroindazole with sodium iodide. The specific preparation method is as follows:
1. Add N-Boc-5-chloroindazole to a compatible solvent, such as dichloromethane.
2. Add sodium iodide at room temperature and stir the reaction mixture well.
3. The reaction is usually carried out for several hours until the completion of the reaction is observed, which can be checked by TLC or other detection methods.

Safety Information:
N-Boc-5-iodine indazole is a chemical reagent, which requires attention to safe operation. Contact or inhalation of the compound may cause irritation or damage to the skin, eyes and respiratory tract. Wear appropriate protective gloves, goggles and masks when using. It should be operated in a well-ventilated place and avoid inhaling its dust or gas. If the skin or eyes are contaminated, rinse immediately with plenty of water and seek medical help. During storage and handling, it should be carried out in accordance with the relevant safety procedures.

Last Update：2024-04-09 20:52:54