10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-
chlorpromazine
CAS: 50-53-3
Molecular Formula: C17H19ClN2S
10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl- - Names and Identifiers
| Name | chlorpromazine |
| Synonyms | 2601-A chlorpromazine Chlorpromazine CHLORPROMAZINE(ALKALI) 3-(2-chlorophenothiazin-10-yl)propyldimethylamine 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl- 3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amine 3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine 2,2',2'',2'''-{[4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo}tetraethanol |
| CAS | 50-53-3 |
| EINECS | 200-045-8 |
| InChI | InChI=1/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H |
10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl- - Physico-chemical Properties
| Molecular Formula | C17H19ClN2S |
| Molar Mass | 318.86 |
| Density | 1.1644 (rough estimate) |
| Melting Point | 56.5°C |
| Boling Point | bp0.8 200-205° |
| Flash Point | 226°C |
| Vapor Presure | 2.72E-08mmHg at 25°C |
| pKa | pKa 9.3(H2O,t =24±1) (Uncertain) |
| Storage Condition | 2-8℃； Avoid light |
| Refractive Index | 1.6230 (estimate) |
| Physical and Chemical Properties | Chlorpromazine Hydrochloride is white or opalescent crystalline powder, with slight odor, bitter taste, hygroscopicity, gradual discoloration in light, acidic reaction in aqueous solution, soluble in water, ethanol or chloroform, insoluble in benzene or ether. |
10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl- - Risk and Safety
| Toxicity | LD50 oral in rat: 142mg/kg |
10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl- - Introduction
This standard substance is mainly used for measuring instrument calibration, analytical method evaluation and quality control, as well as the content determination and residue detection of corresponding components in related fields such as food, hygiene, environment and agriculture. It can also be used for value traceability or as a standard liquid reserve solution. It is diluted step by step and configured into various standard solutions for work. 1. Sample Preparation This standard substance is made of chlorpromazine pure product with accurate purity and fixed value as raw material, chromatographic methanol as solvent, and accurately configured by weight-volume method. Chlorpromazine, English name: Chlorpromazine,CAS number: 50-53-3 2. traceability and setting method This standard substance takes the configuration value as the standard value, and uses high performance liquid chromatography-diode array detector (HPLC -DAD) to compare this batch of standard substances with quality control control samples, and verify the preparation value. By using preparation methods, measurement methods and measuring instruments that meet the requirements of metrological characteristics, the traceability of the value of the standard substance is guaranteed. 3. characteristic value and uncertainty (see certificate) number name standard value (ug/mL) relative expansion uncertainty (%)(k = 2)BW10332 The uncertainty of chlorpromazine 1002 standard value in methanol is mainly composed of raw material purity, weighing, constant volume, uniformity, stability and other uncertainty components. 4. uniformity test and stability inspection According to the JJF1343-2012 [General Principles and Statistical Principles of Standard Substance Setting], random sampling of sub-packed samples is carried out, uniformity test of solution concentration is carried out, and stability inspection is carried out. The results show that the standard material has good uniformity and stability. The standard substance is valid for 24 months from the date of setting the value. The development unit will continue to monitor the stability of the standard substance. If the value changes are found during the validity period, the user will be notified in time. 5. packaging, transportation and storage, use and precautions 1. Packaging: This standard substance is packed in borosilicate glass ampoules, about 1.2 mL/branch. When removing or diluting, the pipette quantity shall prevail. 2. Transportation and storage: normal temperature transportation, transportation should avoid extrusion and collision; Storage under refrigerated (2-8)℃ and protected from light. 3. Use: Balance at room temperature (20±3 ℃) before unsealing, and shake well. Once the ampoule is opened, it should be used immediately and cannot be used as a standard substance after being fused again.
Last Update：2022-10-16 17:25:34
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Product Name: Chlorpromazine Monomer Visit Supplier Webpage Request for quotationCAS: 50-53-3
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple SpecificationsSpot supply
Product Name: Chlorpromazine in methanol Visit Supplier Webpage Request for quotationCAS: 50-53-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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