118276-06-5

118276-06-5 - Names and Identifiers

Name	3,5-Difluoro-4-hydroxybenzaldehyde
Synonyms	2,6-Difluoro-4-formylphenol 3,5-Difluoro-4-hydroxybenzaldehyde 3,5-DIFLUORO-4-HYDROXYBENZALDEHYDE Benzaldehyde,3,5-difluoro-4-hydroxy- Benzaldehyde, 3,5-difluoro-4-hydroxy- (9CI)
CAS	118276-06-5
InChI	InChI=1/C7H4F2O2/c8-5-1-4(3-10)2-6(9)7(5)11/h1-3,11H

118276-06-5 - Physico-chemical Properties

Molecular Formula	C7H4F2O2
Molar Mass	158.1
Density	1.464±0.06 g/cm3(Predicted)
Melting Point	122-124°C
Boling Point	198.5±35.0 °C(Predicted)
Flash Point	73.86°C
Solubility	Chloroform (Slightly), Methanol (Slightly)
Vapor Presure	0.254mmHg at 25°C
Appearance	Crystalline powder
Color	White to Pale Yellow
pKa	5.27±0.23(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Air Sensitive
Refractive Index	1.559
MDL	MFCD06797917
Physical and Chemical Properties	Sensitivity: Air Sensitive

118276-06-5 - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant

118276-06-5 - Introduction

3,5-Difluoro-4-hydroxybenzaldehyde is an organic compound with the chemical formula C7H5F2O2. It is a white solid, soluble in organic solvents such as ethanol and dichloromethane, and insoluble in water.

3,5-difluoro-4-hydroxybenzaldehyde is commonly used as an intermediate in organic synthesis. It can be used for the synthesis of ketone compounds, alcohol compounds, acid compounds and other chemical substances. In the field of medicine, it can also be used to synthesize precursors of some pharmaceutically active moieties.

The method of preparing 3,5-difluoro-4-hydroxybenzaldehyde is usually obtained by reacting the corresponding acid chloride with the corresponding alcohol. Taking 3,5-difluorobenzoic acid chloride as an example, we can react it with the corresponding alcohol, such as p-hydroxybenzyl alcohol, under alkaline conditions to obtain 3,5-difluoro-4-hydroxybenzaldehyde.

Regarding safety information, 3,5-difluoro-4-hydroxybenzaldehyde is an organic compound, and safety precautions should be paid attention to during operation and storage. It may be irritating to the eyes, skin and respiratory tract, so wear appropriate protective equipment during operation, such as lab gloves, goggles and protective masks. In addition, it should be operated in a well-ventilated area and avoid contact with substances such as strong oxidants. Appropriate waste disposal procedures should be followed when handling this compound.

Last Update：2024-04-09 20:52:54