12-BIOTINYLAMINO-4,7,10-TRIOXADODECANOIC ACID N-HYDROXYSUCCINIMIDYL ESTER - Names and Identifiers
Name | Biotin-PEG3-NHS ester
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Synonyms | Biotin-PEG3-SPA Biotin-PEG3-NHS ester (+)-Biotin-PEG3-NHS Ester 12-BIOTINYLAMINO-4,7,10-TRIOXADODECANOIC ACID N-HYDROXYSUCCINIMIDYL ESTER 4,7,10-Trioxa-13-azaoctadecanoic acid, 18-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-14-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
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CAS | 1253286-56-4
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12-BIOTINYLAMINO-4,7,10-TRIOXADODECANOIC ACID N-HYDROXYSUCCINIMIDYL ESTER - Physico-chemical Properties
Molecular Formula | C23H36N4O9S
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Molar Mass | 544.62 |
Density | 1.35±0.1 g/cm3(Predicted) |
pKa | 13.90±0.40(Predicted) |
Storage Condition | 2-8℃ |
12-BIOTINYLAMINO-4,7,10-TRIOXADODECANOIC ACID N-HYDROXYSUCCINIMIDYL ESTER - Introduction
Biotin-PEG3-NHS (Biotin-PEG3-NHS ester) is a compound composed of biotin, triethylene glycol and succinimidyl acrylate.
Its main properties are as follows:
-Appearance: Usually colorless or yellowish solid powder.
-Storage: It should be stored under low temperature and dry conditions, avoiding light and humidity.
-Solubility: Soluble in some organic solvents, such as methanol, dimethyl sulfoxide and dichloromethane.
The main purpose of Biotin-PEG3-NHS ester:
-Biotin labeling: through its affinity with biotin, it is combined with a label (such as a fluorescent dye, enzyme or radioisotope) for fluorescence microscopy, enzyme-linked immunosorbent assay (ELISA) and radioimmunoassay.
-Activation carrier: Use it as an activation carrier to introduce biotin into cells, proteins or other compounds to further study its function, interaction and positioning.
The method for preparing Biotin-PEG3-NHS ester is generally a synthetic method:
1. Biotin is reacted with succinimidyl acrylate to generate biotin-succinimidyl ester.
2. Increase the functional group of triethylene glycol (polyethylene glycol) to react with biotin-succinimide ester to form Biotin-PEG3-NHS ester.
When using Biotin-PEG3-NHS ester, you need to pay attention to its security information:
-Due to the sensitivity and irritation of the compound, contact with skin and eyes may cause irritation. Appropriate protective measures should be taken, such as gloves, goggles and chemical protective clothing.
-It should be operated in a well-ventilated laboratory and avoid inhaling its dust or solution.
-In the event of accidental inhalation or ingestion, seek medical attention immediately and present the safety data sheet (MSDS) for this product.
-Under the correct storage conditions, the Biotin-PEG3-NHS ester has a long stability and service life.
-Before use, you should carefully read the relevant technical information and instructions to ensure correct operation and successful experiment.
Last Update:2024-04-09 21:04:16