1218790-37-4 - Names and Identifiers
Name | 2-(4-Methoxy-2-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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Synonyms | 4-Methoxy-2-(trifluoromethyl)phenylboronic acid, pinacol ester 2-(4-Methoxy-2-trifluoromethyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 2-(4-Methoxy-2-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 1,3,2-Dioxaborolane, 2-[4-methoxy-2-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-
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CAS | 1218790-37-4
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1218790-37-4 - Physico-chemical Properties
Molecular Formula | C14H18BF3O3
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Molar Mass | 302.1 |
Storage Condition | Sealed in dry,2-8°C |
Sensitive | IRRITANT |
MDL | MFCD09746197 |
1218790-37-4 - Introduction
2-(4-Methoxy-2-trifluoromethylphenyl)-4,4,5,5-tetramethyl-1,3, 2-dioxaborane (2-(4-Methoxy-2-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane) is an organic compound. It is a fluorinated aromatic ether compound containing a benzene ring and a methoxy group, and also contains a boron atom.
The properties of this compound are:
-The molecular formula is C15H18BF3O2 and the molecular weight is 299.11g/mol;
-Appearance is white crystalline solid;
-Melting point is approximately 68-72°C;
-can be dissolved in organic solvents, such as dichloromethane, ether, etc.
2-(4-methoxy-2-trifluoromethylphenyl)-4,4, 5,5-tetramethyl -1,3, 2-dioxoborane has a wide range of applications, mainly including:
-As a reagent for organic synthesis, it is used to construct the carbon-boron bond of the compound;
-used to synthesize organometallic compounds, such as intermediates of primary amine-lithium-borane addition system;
-Used in the synthesis of pharmaceutical and pesticide intermediates, as well as the synthesis of chemicals.
The method of preparing 2-(4-methoxy-2-trifluoromethylphenyl)-4,4, 5,5-tetramethyl -1,3, 2-dioxaborane includes:
-The corresponding compound is obtained by the reaction of trifluorotoluene and diborane, and then the acyl chloride reaction is carried out under alkaline conditions;
-The corresponding compound is obtained by a substitution reaction of p-trifluoromethylbromobenzene and an ether compound.
Regarding safety information, the toxicity and safety of 2-(4-methoxy-2-trifluoromethylphenyl)-4,4, 5,5-tetramethyl -1,3, 2-dioxoborane are limited. Use should follow general laboratory safety practices and avoid contact with skin, eyes and respiratory tract. If you are exposed or unwell, you should seek medical assistance immediately. Ensure that you operate in a well-ventilated environment and use appropriate personal protective equipment.
Last Update:2024-04-09 20:02:46