130599-34-7

130599-34-7 - Names and Identifiers

Name	5-(4-TRIFLUOROMETHYL-PHENYL)-2H-PYRAZOL-3-YLAMINE
Synonyms	5-(4-(TrifluoroMethyl)phenyl)-1H-pyrazol-3-aMine 5-[4-(trifluoromethyl)phenyl]-1H-Pyrazol-3-amine 5-(4-TRIFLUOROMETHYL-PHENYL)-2H-PYRAZOL-3-YLAMINE 1H-Pyrazol-3-amine, 5-[4-(trifluoromethyl)phenyl]-
CAS	130599-34-7
InChI	InChI=1S/C10H8F3N3/c11-10(12,13)7-3-1-6(2-4-7)8-5-9(14)16-15-8/h1-5H,(H3,14,15,16)

130599-34-7 - Physico-chemical Properties

Molecular Formula	C10H8F3N3
Molar Mass	227.19
Density	1.401±0.06 g/cm3(Predicted)
Boling Point	405.0±45.0 °C(Predicted)
pKa	13.76±0.10(Predicted)
Storage Condition	2-8°C(protect from light)

130599-34-7 - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	25 - Toxic if swallowed
Safety Description	45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 2811 6.1 / PGIII

130599-34-7 - Introduction

5-(4-Trifluoromethyl)-2H-pyrazol-3-ylamine is an organic compound whose chemical formula is C6H4F3N3. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 5-(4-Trifluoromethyl)-2H-pyrazol-3-ylamine is a colorless or pale yellow crystalline solid.
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and dichloromethane, soluble in water under acidic conditions.

Use:
- 5-(4-Trifluoromethyl)-2H-pyrazol-3-ylamine is widely used in organic synthesis and medicine. It can be used as a light stabilizer, a chelating agent, a biologically active molecular sieve agent, etc.
-In the field of medicine, it has anti-cancer, anti-inflammatory and antibacterial effects, commonly used in drug research and synthesis.

Preparation Method:
The preparation method of -5-(4-trifluoromethyl)-2H-pyrazol-3-ylamine can be carried out by the following steps:
1. reacting imidazole with trifluoromethyl ammonium iodide to generate 4-trifluoromethyl imidazole.
2. Reaction of 4-trifluoromethylimidazole with an amino compound to generate 5-(4-trifluoromethyl)-2H-pyrazol-3-ylamine.

Safety Information:
- 5-(4-trifluoromethyl)-2H-pyrazol-3-ylamine is an organic compound, which should be operated safely.
-Without special instructions, generally avoid contact with skin and eyes, and avoid inhalation or ingestion.
-Strictly follow the relevant safety procedures during use, and store and handle the compound properly. If necessary, refer to the relevant safety information or consult a professional.

Last Update：2024-04-09 02:00:41