132144-03-7

132144-03-7 - Names and Identifiers

Name	6-(1-Piperazinyl)-3-pyridinecarboxylic acid methyl ester
Synonyms	Methyl 6-(piperazin-1-yl)nicotinate methyl 6-(piperazin-1-yl)nicotinate tert-butyl 6-(piperazin-1-yl)nicotinate 6-(1-Piperazinyl)-3-pyridinecarboxylic acid methyl ester 3-Pyridinecarboxylic acid, 6-(1-piperazinyl)-, methyl ester
CAS	132144-03-7

132144-03-7 - Physico-chemical Properties

Molecular Formula	C11H15N3O2
Molar Mass	221.26
Density	1.171±0.06 g/cm3(Predicted)
Melting Point	165～167℃
Boling Point	395.0±37.0 °C(Predicted)
pKa	8.52±0.10(Predicted)
Storage Condition	Room Temprature

132144-03-7 - Introduction

6-(1-Piperazinyl)-3-pyridinecarboxylic acid methyl ester is an organic compound with the chemical formula C12H16N2O2. The following is a description of its nature, use, preparation and safety information:

Nature:
6-(1-Piperazinyl)-3-pyridinecarboxylic acid methyl ester is a white crystalline solid, soluble in organic solvents such as ethanol and dichloromethane. It has medium to high stability.

Use:
6-(1-Piperazinyl)-3-pyridinecarboxylic acid methyl ester is widely used in the field of medicine and is often used as a reagent or intermediate. It can be used to synthesize a variety of drugs, such as antipsychotics, antidepressants and antiepileptic drugs.

Method:
The common method for the preparation of 6-(1-Piperazinyl)-3-pyridinecarboxylic acid methyl ester is to react piperazine with methyl nicotinate. The specific preparation method may be to dissolve piperazine in an appropriate amount of solvent, then add an appropriate amount of methyl nicotinate, and after a period of reaction, filter, wash and dry to obtain the product.

Safety Information:
Regarding the toxicity and safety of 6-(1-Piperazinyl)-3-pyridinecarboxylic acid methyl ester, it must be handled with care. It is an irritant substance and requires the wearing of suitable protective equipment, including gloves, eye protection and laboratory coats. In addition, avoid inhaling, chewing or eating, and ensure that the laboratory has a good ventilation system. If contact with skin or eyes occurs, rinse immediately with plenty of water and seek medical assistance. The use of any chemical should be carried out in accordance with safe practices and in accordance with the safety data sheets provided by the manufacturer.

Last Update：2024-04-09 21:54:55