1436389-34-2 - Names and Identifiers
| Name | 2-(4'-bromo-[1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid
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| Synonyms | 2-(4'-bromo-[1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid
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| CAS | 1436389-34-2
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1436389-34-2 - Introduction
2-(4 '-bromo-[1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid is an organic compound with the chemical formula C14H9BrF2O2. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White to yellowish Crystal
-Melting point: about 170-172 ° C
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and chloroform, slightly soluble in water
Use:
- 2-(4 '-bromo-[1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid is often used as an important intermediate and reagent in organic synthesis.
-It can be used to synthesize biologically active compounds, such as drugs, pesticides and fungicides.
Method:
2-(4 '-bromo-[1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid can be synthesized by the following steps:
1. First, 4 '-bromo-[1,1'-biphenyl]-4-ylcarbaldehyde reacts with ammonia and hydrofluoric acid to generate the corresponding amide.
2. The amide was then reacted with sodium hydroxide and difluoric anhydride to give the target product 2-(4 '-bromo-[1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid.
Safety Information:
- 2-(4 '-bromo-[1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid is an organic compound, it should be operated under the guidance of a chemical laboratory or professional.
-Wear personal protective equipment such as goggles, gloves and lab coats when using.
-avoid contact with skin, eyes and respiratory tract, such as accidental contact, please rinse immediately with plenty of water.
-Use in a well-ventilated place, and away from fire and hot spots.
Please pay attention to the use of safety measures, and according to the specific situation and needs of reasonable experimental operation.
Last Update：2024-04-09 21:01:54