1472611-44-1 - Names and Identifiers
1472611-44-1 - Physico-chemical Properties
Molecular Formula | C33H33F3N8O7
|
Molar Mass | 710.67 |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Use | CAS:1085412-37-8 (free base) |
In vitro study | Pyridostatin reduces proliferation of MRC-5-SV40 cells and various cancer cell lines and induces cell cycle arrest through activation of the DNA damage checkpoint. Pyridostatin also reduces SRC-dependent cell motility in MDA-MB-231 cells by interacting with G-quadruplex in SRC. Pyridostatin reduces EBNA1 synthesis by inhibiting G-quadruplex. |
1472611-44-1 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 0 ml | 0 ml | 0 ml |
5 mM | 0 ml | 0 ml | 0 ml |
10 mM | 0 ml | 0 ml | 0 ml |
5 mM | 0 ml | 0 ml | 0 ml |
Last Update:2024-01-02 23:10:35
1472611-44-1 - Reference Information
biological activity | Pyridostatin Trifluoroacetate Salt (RR82) is a G-quadruplexe stabilizer with a Kd of 490 nM in a cell-free assay, it targets a series of proto-oncogenes. |
Target | Value |
G-quadruplexe
(Cell-free assay)
| 490 nM(Kd) |
Last Update:2024-04-09 21:11:58