15(R)-PROSTAGLANDIN E1 - Names and Identifiers
15(R)-PROSTAGLANDIN E1 - Physico-chemical Properties
Molecular Formula | C20H34O5
|
Molar Mass | 354.48 |
Density | 1.131±0.06 g/cm3(Predicted) |
Boling Point | 529.3±50.0 °C(Predicted) |
pKa | 4.77±0.10(Predicted) |
Storage Condition | -20°C |
15(R)-PROSTAGLANDIN E1 - Introduction
15(R)-PROSTAGLANDIN E1(15(R)-PGE1) is a natural lipid-like compound, also known as prostacyclin E1. It is a prostaglandin with a specific stereo configuration and has a wide range of biological activities.
Nature:
15(R)-PGE1 is a colorless to light yellow solid with water-insoluble properties. It is a low toxicity and relatively stable compound.
Use:
1. Drug treatment: 15(R)-PGE1 is widely used in the medical field, especially as a therapeutic agent to expand coronary arteries and treat angina pectoris and myocardial infarction.
2. Oxytocin: 15(R)-PGE1 is also used as oxytocin to promote contractions and childbirth.
Preparation Method:
15(R)-PGE1 can be prepared by chemical synthesis. One commonly used method is to catalyze the asymmetric synthesis of precursor compounds by using a suitable catalyst to give 15(R)-pge1.
Safety Information:
15(R)-PGE1 is generally safe under normal doses, but the following matters should be paid attention to during use:
1. Before use should carefully read the relevant drug instructions, and use the dose according to the doctor's advice.
2. Some patients may be allergic to 15(R)-PGE1, and the possibility of allergic reaction should be paid attention to when using.
3. Should avoid interaction with other drugs, especially anticoagulants and thrombolytic drugs.
4. During use, if there are serious side effects or adverse reactions, you should stop using it immediately and seek medical advice.
Last Update:2024-04-09 02:00:54