Name | 16α,17-epoxy-11α-hydroxypregn-4-ene-3,20-dione |
Synonyms | 11A-HYDROXY EPOXY PROGESTERONE 11 alpha-hydroxy Epoxy progesterone 16a,17-Epoxy-11a-hydroxypregn-4-ene 11a-Hydroxy-16,17a-epoxyprogesterone 11A-HYDROXY 16,17A-EPOXY PROGESTERONE 4-Pregnene-16α,17α-epoxy-11β-ol-3,20-dione 11-hydroxy-16,17-epoxypregn-4-ene-3,20-dione 16a,17-epoxy-11a-hydroxypregn-4-ene-3,20-dione 16A,17A-EPOXY-11A-HYDROXY-4-PREGNEN-3,20-DIONE 16α,17-epoxy-11α-hydroxypregn-4-ene-3,20-dione 11alpha-Hydroxy-16alpha,17alpha Epoxy Progesterone 16alpha,17-epoxy-11alpha-hydroxypregn-4-ene-3,20-dione (11alpha,16alpha)-11-hydroxy-16,17-epoxypregn-4-ene-3,20-dione |
CAS | 19427-36-2 |
EINECS | 243-049-5 |
InChI | InChI=1/C21H28O4/c1-11(22)21-17(25-21)9-15-14-5-4-12-8-13(23)6-7-19(12,2)18(14)16(24)10-20(15,21)3/h8,14-18,24H,4-7,9-10H2,1-3H3/t14-,15-,16+,17+,18+,19-,20-,21+/m0/s1 |
Molecular Formula | C21H28O4 |
Molar Mass | 344.44 |
Density | 1.25±0.1 g/cm3(Predicted) |
Melting Point | 238.0-238.5 °C(Solv: benzene (71-43-2); cyclohexane (110-82-7)) |
Boling Point | 508.7±50.0 °C(Predicted) |
Flash Point | 178.651°C |
Solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
Vapor Presure | 0mmHg at 25°C |
Appearance | Solid |
Color | White to Off-White |
pKa | 14.42±0.70(Predicted) |
Storage Condition | Refrigerator |
Refractive Index | 1.586 |
Physical and Chemical Properties | Melting point> 234 °c (247-249 °c). |
Use | Used as a steroid hormone Intermediate |
uses | intermediates of cortisone acetate and skin ease acetate. Used as steroid hormone intermediate |
production method | the product can be prepared by reaction of diosgenin through ring opening, acetylation, oxidation, hydrolysis, elimination, epoxidation, oxidation, etc. |