Molecular Formula | C22H32O5 |
Molar Mass | 376.49 |
Physical and Chemical Properties | Chemical property crystallization (acetone), melting point> 210 ℃. |
Use | Use an intermediate of dexamethasone acetate. |
Use 3 β-hydroxygestrol -5,16-diene -20-one -3-acetate (I. e. dienolone acetate) via (nitrosomethyl urea on the 16-position double bond) Addition and elimination to generate 3 β-hydroxy-16 β-methylgestrol -5,16-diene -20-one -3-acetate, and then pass (16,17-position) epoxidation, (3-position hydroxyl) acetylation, (epoxy) ring opening to form 17 α-hydroxyl and 15-position double bond, (15-position double bond) hydrogenation, hydrolysis (Deacetylation), oxidation (3-position hydroxyl, 5-position double bond to 4-position),(21-position) iodization,(21-position iodine) conversion to obtain 17,21-dihydroxy -16 β-methylpregnan-4-ene-3, 20-dike-21-acetate, and finally the product is made by mold oxidation.