182287-63-4 - Names and Identifiers
182287-63-4 - Physico-chemical Properties
182287-63-4 - Upstream Downstream Industry
182287-63-4 - Introduction
4-(Bromomethyl)-3-iodobenzonitrile, chemical name is 4-(Bromomethyl)-3-iodobenzonitrile, molecular formula is C9H5BrIN, relative molecular mass is 333.95g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
4-(Bromomethyl)-3-iodobenzonitrile is a white crystalline solid with a strong odor. It has low solubility at room temperature and is almost insoluble in water, but can be dissolved in some organic solvents. Its melting point is about 100°C.
Use:
4-(Bromomethyl)-3-iodobenzonitrile is an organic intermediate compound, which is widely used in the fields of medicine, pesticide and material science. It is often used as a raw material or reaction intermediate in organic synthesis for the synthesis of various organic compounds.
Method:
The usual preparation method is carried out by the sequence of iodination, Bromination and amine cyanation. First, 2-iodomethylbenzene is reacted with nitrous acid to obtain p-nitrobenzoic acid. Then, under appropriate conditions, P-nitrobenzoic acid is reacted with brominated sulfoxide to give 4-bromo-2-nitrobenzoyl bromide. Finally, 4-bromo-2-nitrobenzoyl bromide was converted to 4-(Bromomethyl)-3-iodobenzonitrile using an amine Cyanogen reaction.
Safety Information:
4-(Bromomethyl)-3-iodobenzonitrile should pay attention to safety during use and storage. It may be irritating to the eyes and skin, so avoid contact when handling. In addition, the compound may be toxic and should be kept away from children, away from heat and fire sources, and handled in a well-ventilated area. Use appropriate personal protective equipment such as safety glasses, gloves and protective clothing. When handling and storing the compound, the relevant safe operating guidelines and regulations should be followed.
Last Update:2024-04-09 21:01:54