18437-72-4
(4-Fluorophenyl)diphenylphosphane
CAS: 18437-72-4
Molecular Formula: C18H14FP
18437-72-4 - Names and Identifiers
| Name | (4-Fluorophenyl)diphenylphosphane |
| Synonyms | (4-Fluorophenyl)diphenylphosphane Phosphine, (4-fluorophenyl)diphenyl- |
| CAS | 18437-72-4 |
18437-72-4 - Physico-chemical Properties
| Molecular Formula | C18H14FP |
| Molar Mass | 280.28 |
| Boling Point | 357.4±25.0 °C(Predicted) |
18437-72-4 - Introduction
(4-Fluorophenyl)diphenylphosphane, also known as (4-Fluorophenyl)diphenylphosphane, is an organophosphorus compound. Its chemical formula is C18H14FP and its molecular weight is 284.3g/mol.
(4-Fluorophenyl)diphenylphosphane is a white to pale yellow crystalline solid that does not smell at room temperature. It has good solubility in organic solvents such as ether and dimethylformamide. The compound has good thermal stability and air stability.
(4-Fluorophenyl)diphenylphosphane has a wide range of applications. It can be used as a ligand for catalytic reactions in organic synthetic chemistry, such as palladium-catalyzed cross-coupling reactions. It can also be used for synthetic reactions in metal organic chemistry, such as palladium-catalyzed Suzuki coupling reactions. In addition, it can also play an important role in the preparation of drug synthesis and functional materials.
The preparation method of (4-Fluorophenyl)diphenylphosphane is usually obtained by reacting p-phenyltrifluoroborane and phenyldibromomethane. During the reaction, the two compounds undergo an exchange reaction in the presence of a base to produce the desired product.
Regarding safety information,(4-Fluorophenyl)diphenylphosphane is a chemical and should be handled in accordance with safe operating procedures. It may irritate the skin, eyes and respiratory system, so pay attention to protective measures when touching and using. Inhalation, chewing or swallowing of the compound should be avoided as much as possible during the procedure. If you come into contact with this substance, rinse immediately with plenty of water and seek medical advice.
(4-Fluorophenyl)diphenylphosphane is a white to pale yellow crystalline solid that does not smell at room temperature. It has good solubility in organic solvents such as ether and dimethylformamide. The compound has good thermal stability and air stability.
(4-Fluorophenyl)diphenylphosphane has a wide range of applications. It can be used as a ligand for catalytic reactions in organic synthetic chemistry, such as palladium-catalyzed cross-coupling reactions. It can also be used for synthetic reactions in metal organic chemistry, such as palladium-catalyzed Suzuki coupling reactions. In addition, it can also play an important role in the preparation of drug synthesis and functional materials.
The preparation method of (4-Fluorophenyl)diphenylphosphane is usually obtained by reacting p-phenyltrifluoroborane and phenyldibromomethane. During the reaction, the two compounds undergo an exchange reaction in the presence of a base to produce the desired product.
Regarding safety information,(4-Fluorophenyl)diphenylphosphane is a chemical and should be handled in accordance with safe operating procedures. It may irritate the skin, eyes and respiratory system, so pay attention to protective measures when touching and using. Inhalation, chewing or swallowing of the compound should be avoided as much as possible during the procedure. If you come into contact with this substance, rinse immediately with plenty of water and seek medical advice.
Last Update：2024-04-09 20:44:15
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