185996-33-2 - Names and Identifiers
| Name | (S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-ACETAMIDE
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| Synonyms | (S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-ACETAMIDE
1,3-DIOXOLANE-4-ACETAMIDE, 2,2-DIMETHYL-, (S)
1,3-DIOXOLANE-4-ACETAMIDE, 2,2-DIMETHYL-, (4S)-
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| CAS | 185996-33-2
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185996-33-2 - Physico-chemical Properties
| Molecular Formula | C7H13NO3
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| Molar Mass | 159.18 |
| Density | 1.2013 (rough estimate) |
| Melting Point | 108-109 °C |
| Boling Point | 284.67°C (rough estimate) |
| Refractive Index | 1.4452 (estimate) |
185996-33-2 - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes.
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185996-33-2 - Upstream Downstream Industry
185996-33-2 - Introduction
(S)-2,2-dimethyl-1, 3-DIOXOLANE-4-ACETAMIDE is an organic compound with the chemical formula C8H15NO3. Its main properties are as follows:
1. Appearance: It is a colorless liquid.
2. Solubility: The compound is insoluble in water, but soluble in many commonly used organic solvents, such as ethanol, acetone, etc.
3. Boiling point: Its boiling point is about 155-156°C.
4. Density: its density is about 1.020g/cm3.
5. Optical activity: The compound is chiral and exists in two enantiomers, namely (S)-and (R)-forms.
One of the main uses of (S)-2,2-dimethyl-1, 3-DIOXOLANE-4-ACETAMIDE is as a reagent in organic synthesis. It can be used as a catalyst, ligand or raw material to participate in a variety of chemical reactions, such as esterification, etherification, acylation and other reactions. In addition, it is also used as an intermediate in the synthesis of pesticides and pharmaceuticals.
The method of preparing the compound can be carried out by the following steps:
1. First, 2,2-dimethyl -1,3-dioxopentanol (2,2-dimethyl-1, 3-dioxolane) was reacted with bromoacetic acid to obtain 2,2-dimethyl -1, 3-dioxol-4-acetic acid (2,2-dimethy1-1,3-dioxolane-4-acetic acid).
2. Then, the above product is reacted with sodium hypochlorite (sodium hypochlorite) to obtain (S)-2,2-dimethyl-1,3-dioxolane-4-acetic acid ((S)-2,2-dimethyl-1, 3-dioxolane-4-acetic acid).
3. Finally, the above product is condensed with aldehyde to obtain the final product (S)-2,2-dimethyl-1, 3-DIOXOLANE-4-ACETAMIDE. This step requires the use of appropriate condensing agents and catalysts.
With regard to safety information, specific information may be limited as specific toxicity and hazard data are not available. However, in general, appropriate laboratory safety measures should be taken when handling the compound, including wearing gloves, goggles and laboratory coats to protect the skin and eyes, while maintaining good ventilation conditions. Laboratory safety procedures and recommendations should be followed when using or handling the compound. For more detailed safety information, please refer to the safety data sheet (SDS) of the compound or consult a professional body.
Last Update：2024-04-09 21:04:16