1H-Imidazole, 2-(4-fluorophenyl)-

1H-Imidazole, 2-(4-fluorophenyl)- - Names and Identifiers

Name	2-(4-Fluoro-Phenyl)-1H-Imidazole
Synonyms	868764 2-(4-Fluorophenyl)imidazole 2-(4-Fluoro-Phenyl)-1H-Imidazole 2-(4-FLUORO-PHENYL)-1H-IMIDAZOLE 1H-Imidazole, 2-(4-fluorophenyl)-
CAS	4278-08-4

1H-Imidazole, 2-(4-fluorophenyl)- - Physico-chemical Properties

Molecular Formula	C9H7FN2
Molar Mass	162.16
Density	1.242±0.06 g/cm3(Predicted)
Melting Point	196-198 °C
Boling Point	332.2±25.0 °C(Predicted)
pKa	12.90±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature

1H-Imidazole, 2-(4-fluorophenyl)- - Risk and Safety

Risk Codes	41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.

1H-Imidazole, 2-(4-fluorophenyl)- - Introduction

2-(4-Fluoro-Phenyl)-1H-Imidazole is an organic compound with the chemical formula C9H7FN2. It is a white crystalline solid, soluble in organic solvents such as acetonitrile, dichloromethane and the like. It has an imidazole ring and a 4-fluorobenzene group, which makes it have a wide range of applications in the fields of medicine and material science.

2-(4-Fluoro-Phenyl)-1H-Imidazole has been studied as a potential antibacterial, anti-inflammatory and anti-tumor agent in the field of medicine. It can interfere with some bioactive molecules in the cell, thereby inhibiting cell growth and reproduction. In addition, it can also be used as a starting material for the synthesis of other compounds, such as organic fluorescent dyes, coordination compounds, etc.

The preparation method of 2-(4-Fluoro-Phenyl)-1H-Imidazole can be obtained by a condensation reaction between imidazole and 4-fluoronitrobenzene. The specific preparation method may be reacting 4-fluoronitrobenzene and imidazole in a solvent under alkaline conditions, followed by distillation, crystallization and purification to obtain the target product.

Regarding safety information, there are currently no special safety warnings for 2-(4-Fluoro-Phenyl)-1H-Imidazole. However, appropriate laboratory safety measures should be taken during operation, such as wearing protective glasses, gloves and laboratory coats, avoiding contact with skin and inhalation of gases. In addition, it should be operated in a well-ventilated place to avoid the accumulation of dust or gas. During storage, the compound should be stored in a dry, cool place, away from ignition and flammable materials. Proper chemical waste disposal procedures should be followed when using and handling this compound.

Last Update：2024-04-09 20:52:54