1H-Indole, 6-fluoro-2-Methyl-
6-fluoro-2-methyl-1H-indole
CAS: 40311-13-5
Molecular Formula: C9H8FN
1H-Indole, 6-fluoro-2-Methyl- - Names and Identifiers
| Name | 6-fluoro-2-methyl-1H-indole |
| Synonyms | 106158 6-Flioro-2methylindole 6-FLUORO-2-METHYLINDOLE 6-fluoro-2-methyl-1H-indole 1H-Indole, 6-fluoro-2-Methyl- |
| CAS | 40311-13-5 |
| InChI | InChI=1/C9H8FN/c1-6-4-7-2-3-8(10)5-9(7)11-6/h2-5,11H,1H3 |
1H-Indole, 6-fluoro-2-Methyl- - Physico-chemical Properties
| Molecular Formula | C9H8FN |
| Molar Mass | 149.16 |
| Density | 1.219 |
| Melting Point | 100 |
| Boling Point | 269℃ |
| Flash Point | 117℃ |
| Vapor Presure | 0.012mmHg at 25°C |
| pKa | 16.97±0.30(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.627 |
1H-Indole, 6-fluoro-2-Methyl- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Note | Irritant |
1H-Indole, 6-fluoro-2-Methyl- - Introduction
6-fluoro-2-methyl-1H-indole is an organic compound with the chemical formula C9H8FN. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 6-fluoro-2-methyl-1H-indole is a white to pale yellow solid.
-Melting point: about 80-85°C.
-Boiling point: about 245-247°C.
-Solubility: Good solubility in organic solvents.
Use:
6-fluoro-2-methyl-1H-indole is widely used as an intermediate for the synthesis of drugs in medicinal chemistry. It can be used as a building block of drug molecules, with good variability and activity.
Preparation Method:
The preparation of 6-fluoro-2-methyl-1H-indole is usually carried out by synthetic chemical methods. One of the commonly used methods is to react 2-methylindole with a fluorinating agent under specific reaction conditions to produce 6-fluoro-2-methyl-1H-indole.
Safety Information:
Regarding the safety of 6-fluoro-2-methyl-1H-indole, there is currently not much specific research information on this compound. However, in general, when using and handling organic compounds, appropriate safety measures should be taken, such as wearing protective gloves and glasses, and handling in a well-ventilated area. In addition, the compound should be stored and disposed of properly to avoid contact with strong oxidants or strong acids.
Due to the diversity of the characteristics and use of chemical substances, please strictly follow the relevant laws and regulations, and follow the appropriate operating procedures and safe operating procedures in experimental or industrial applications.
Nature:
-Appearance: 6-fluoro-2-methyl-1H-indole is a white to pale yellow solid.
-Melting point: about 80-85°C.
-Boiling point: about 245-247°C.
-Solubility: Good solubility in organic solvents.
Use:
6-fluoro-2-methyl-1H-indole is widely used as an intermediate for the synthesis of drugs in medicinal chemistry. It can be used as a building block of drug molecules, with good variability and activity.
Preparation Method:
The preparation of 6-fluoro-2-methyl-1H-indole is usually carried out by synthetic chemical methods. One of the commonly used methods is to react 2-methylindole with a fluorinating agent under specific reaction conditions to produce 6-fluoro-2-methyl-1H-indole.
Safety Information:
Regarding the safety of 6-fluoro-2-methyl-1H-indole, there is currently not much specific research information on this compound. However, in general, when using and handling organic compounds, appropriate safety measures should be taken, such as wearing protective gloves and glasses, and handling in a well-ventilated area. In addition, the compound should be stored and disposed of properly to avoid contact with strong oxidants or strong acids.
Due to the diversity of the characteristics and use of chemical substances, please strictly follow the relevant laws and regulations, and follow the appropriate operating procedures and safe operating procedures in experimental or industrial applications.
Last Update：2024-04-09 21:54:55
