Molecular Formula | C16H11BrN2O2 |
Molar Mass | 343.17 |
Density | 1.567±0.06 g/cm3(Predicted) |
Boling Point | 527.3±50.0 °C(Predicted) |
Solubility | DMSO |
Appearance | powder |
Color | white to beige |
pKa | 12.57±0.10(Predicted) |
Storage Condition | 2-8°C |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.914 ml | 14.57 ml | 29.14 ml |
5 mM | 0.583 ml | 2.914 ml | 5.828 ml |
10 mM | 0.291 ml | 1.457 ml | 2.914 ml |
5 mM | 0.058 ml | 0.291 ml | 0.583 ml |
biological activity | Anle138b is a novel oligomer modulator and aggregation inhibitor, formation of pathological aggregates of prion protein (PrP (SC)) and alpha-synuclein (alpha-syn) can be prevented. Anle138b had good oral bioavailability, blood brain barrier permeability and no toxicity was detected. Anle138b presents a new therapy for disease-modifying treatment in neurodegenerative diseases such as prion Virus, Parkinson's disease, etc. |
Target | Value |