1H-Pyrazole-3-carboxylic acid, 4-formyl-, methyl ester
Methyl 4-formyl-1H-pyrazole-5-carboxylate
CAS: 35344-93-5
Molecular Formula: C6H6N2O3
1H-Pyrazole-3-carboxylic acid, 4-formyl-, methyl ester - Names and Identifiers
| Name | Methyl 4-formyl-1H-pyrazole-5-carboxylate |
| Synonyms | Methyl 4-formyl-1H-pyrazole-5-carboxylate 1H-Pyrazole-3-carboxylic acid, 4-formyl-, methyl ester |
| CAS | 35344-93-5 |
1H-Pyrazole-3-carboxylic acid, 4-formyl-, methyl ester - Physico-chemical Properties
| Molecular Formula | C6H6N2O3 |
| Molar Mass | 154.12 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD19103345 |
1H-Pyrazole-3-carboxylic acid, 4-formyl-, methyl ester - Introduction
Methyl is an organic compound with the chemical formula C8H7N3O3. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Methyl is white to light yellow crystal powder.
-Melting point: Its melting point is about 102-106°C.
-Solubility: Can be dissolved in some organic solvents, such as dichloromethane, ethanol and methanol.
-Stability: relatively stable at room temperature.
Use:
Methyl has certain application value in organic synthesis:
-as a reagent: can be used as a reagent in organic synthesis, such as: for the synthesis of pyrazole compounds.
-Drug research: Its structure contains acyl and carboxylate functional groups, which can be used as raw materials for new drugs.
Preparation Method:
Methyl can generally be synthesized:
First, peracetic acid is used to oxidize p-methylaniline to obtain p-formylaniline. It is then reacted with an α-hydroxy ketone, such as acetylacetone, to form pyrazolone. Finally, methanol is added for the acylation reaction to give the final product.
Safety Information:
The specific toxicity and hazards of Methyl are not fully understood. However, as a chemical substance, it is generally necessary to take appropriate safety measures:
-Avoid inhaling its dust or gas, and operate in a well-ventilated place.
-Avoid contact with skin and eyes and wear appropriate protective gloves and goggles.
-If exposed, rinse immediately with plenty of water and seek medical help.
-Store away from fire and oxidant and keep a sealed, dry environment.
Please note that the information provided here is for reference only. Please follow the relevant chemical operating regulations and safety precautions when using it in practice.
Nature:
-Appearance: Methyl is white to light yellow crystal powder.
-Melting point: Its melting point is about 102-106°C.
-Solubility: Can be dissolved in some organic solvents, such as dichloromethane, ethanol and methanol.
-Stability: relatively stable at room temperature.
Use:
Methyl has certain application value in organic synthesis:
-as a reagent: can be used as a reagent in organic synthesis, such as: for the synthesis of pyrazole compounds.
-Drug research: Its structure contains acyl and carboxylate functional groups, which can be used as raw materials for new drugs.
Preparation Method:
Methyl can generally be synthesized:
First, peracetic acid is used to oxidize p-methylaniline to obtain p-formylaniline. It is then reacted with an α-hydroxy ketone, such as acetylacetone, to form pyrazolone. Finally, methanol is added for the acylation reaction to give the final product.
Safety Information:
The specific toxicity and hazards of Methyl are not fully understood. However, as a chemical substance, it is generally necessary to take appropriate safety measures:
-Avoid inhaling its dust or gas, and operate in a well-ventilated place.
-Avoid contact with skin and eyes and wear appropriate protective gloves and goggles.
-If exposed, rinse immediately with plenty of water and seek medical help.
-Store away from fire and oxidant and keep a sealed, dry environment.
Please note that the information provided here is for reference only. Please follow the relevant chemical operating regulations and safety precautions when using it in practice.
Last Update：2024-04-09 20:45:29
