1H-Pyrazole-5-carboxylic acid, 1-methyl-3-phenyl-

1H-Pyrazole-5-carboxylic acid, 1-methyl-3-phenyl- - Names and Identifiers

Name	1-METHYL-3-PHENYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
Synonyms	5-Carboxy-1-methyl-3-phenyl-1H-pyrazole 1-METHYL-3-PHENYL-1H-PYRAZOLE-5-CARBOXYLIC ACID 1H-Pyrazole-5-carboxylic acid, 1-methyl-3-phenyl-
CAS	10250-64-3

1H-Pyrazole-5-carboxylic acid, 1-methyl-3-phenyl- - Physico-chemical Properties

Molecular Formula	C11H10N2O2
Molar Mass	202.209
Density	1.24±0.1 g/cm3(Predicted)
Melting Point	186 °C
Boling Point	419.6±33.0 °C(Predicted)
pKa	2.97±0.25(Predicted)
Storage Condition	2-8°C

1H-Pyrazole-5-carboxylic acid, 1-methyl-3-phenyl- - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R36 - Irritating to the eyes
WGK Germany	3

1H-Pyrazole-5-carboxylic acid, 1-methyl-3-phenyl- - Upstream Downstream Industry

Raw Materials

1-Methyl-3-phenylpyrazol-5-carbonsaeure-methylester
METHYL 2,4-DIOXO-4-PHENYLBUTANOATE
5-PHENYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER
ETHYL 1-METHYL-3-PHENYL-1H-PYRAZOLE-5-CARBOXYLATE
ETHYL 2,4-DIOXO-4-PHENYLBUTANOATE
METHYL-3-AMINO-1-METHYL PYRAZOLE-5-CARBOXYLATE
Phenylboronic acid
Acetophenone

1H-Pyrazole-5-carboxylic acid, 1-methyl-3-phenyl- - Introduction

ACID is an organic compound with the chemical formula C11H10N2O2.

The properties of this compound are as follows:
1. Appearance: colorless crystalline solid
2. Melting Point: 173-174 ° C
3. Solubility: soluble in most organic solvents, such as methanol, ethanol and acetone, slightly soluble in water.

The main uses of ACID are as follows:
1. Chemical intermediates: can be used as intermediates for the synthesis of pesticides, drugs and dyes and other organic compounds.
2. Biological activity Research: It can be used for biological activity research, such as drug design and synthesis of synthetic pyrazole-3-carboxylic acid compounds.

The preparation methods of ACID are mainly as follows:
1. Synthesis of pyrazole ring: through the synthesis reaction of pyrazole ring preparation, a commonly used synthesis method is through the condensation reaction of amino compounds and ketone compounds to generate pyrazole ring.
2. Introduction of carboxyl group: A carboxyl group is introduced into the pyrazole ring by acylation reaction.

Regarding safety information, there is no public assessment report on the specific toxicity and harmfulness of ACID. However, organic compounds generally require appropriate protective measures, such as wearing protective glasses and gloves, to ensure that they are handled in a well-ventilated laboratory. Also, avoid inhaling, chewing, or touching your skin and eyes. If contact occurs, rinse immediately with plenty of water and seek medical attention.

Last Update：2024-04-09 21:11:58