1H-Pyrrole-2-carboxylic acid, 4-formyl-1-methyl-, methyl ester - Names and Identifiers
1H-Pyrrole-2-carboxylic acid, 4-formyl-1-methyl-, methyl ester - Physico-chemical Properties
Molecular Formula | C8H9NO3
|
Molar Mass | 167.16 |
Density | 1.16±0.1 g/cm3(Predicted) |
Melting Point | 100 °C |
Boling Point | 293.1±25.0 °C(Predicted) |
Flash Point | 131.1°C |
Vapor Presure | 0.00176mmHg at 25°C |
pKa | -9.84±0.70(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.521 |
1H-Pyrrole-2-carboxylic acid, 4-formyl-1-methyl-, methyl ester - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
|
Hazard Class | IRRITANT |
1H-Pyrrole-2-carboxylic acid, 4-formyl-1-methyl-, methyl ester - Introduction
Methyl is an organic compound with the chemical formula C8H9NO3. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: methyl l for colorless to light yellow liquid.
-Melting point: about -4 ℃.
-Boiling point: about 233 ℃.
-Solubility: Soluble in organic solvents such as ethanol, dimethyl sulfoxide and acetone.
Use:
methyl l is an important organic synthesis intermediate, widely used in the synthesis of drugs and pesticides. It can also be used as an ingredient in dyes and paints, and as a catalyst for some organic synthesis reactions.
Preparation Method:
The preparation of methyl l can be completed by the following steps:
1. Reaction of methyl 4-methylpyrrole-2-carboxylate with methanol to obtain methyl 4-formate -1-methylpyrrole-2-carboxylate.
2. Subsequently, this product is reacted with an oxidizing agent, such as 2-iodophenyl bromide, to obtain methyl bromide.
Safety Information:
for the safe use of methyl l: pay attention to the following matters:
-It is an organic solvent, which may irritate the skin and eyes, so direct contact should be avoided when using it.
-Use in a well-ventilated area and wear appropriate protective equipment, such as gloves, goggles and respiratory protection.
-Avoid inhaling its vapor, and avoid dust and mist as much as possible.
-Observe relevant safety procedures during use and storage.
Last Update:2024-04-09 20:49:11