1H-imidazole-2-carboxaldehyde, 4-methyl-

1H-imidazole-2-carboxaldehyde, 4-methyl- - Names and Identifiers

Name	4-methyl-1H-imidazole-2-carbaldehyde
Synonyms	BIO-FARMA BF003069 2-PHENYL-THIAZOL-5-YLMETHYLAMINE HCL 4-methyl-1H-imidazole-2-carbaldehyde 5-Methyl-1H-imidazole-2-carbaldehyde 1H-Imidazole-2-carboxaldehyde, 4-methyl- 1H-imidazole-2-carboxaldehyde, 4-methyl- 1H-Imidazole-2-carboxaldehyde, 4-methyl- (9CI) 2-PHENYL-THIAZOL-5-YL-METHYLAMINE HYDROCHLORIDE [(2-PHENYL-1,3-THIAZOL-5-YL)METHYL]AMINEHYDROCHLORIDE
CAS	113825-16-4
InChI	InChI=1/C5H6N2O/c1-4-2-6-5(3-8)7-4/h2-3H,1H3,(H,6,7)

1H-imidazole-2-carboxaldehyde, 4-methyl- - Physico-chemical Properties

Molecular Formula	C5H6N2O
Molar Mass	110.11
Density	1.238±0.06 g/cm3(Predicted)
Melting Point	140-145°C
Boling Point	298.8±33.0 °C(Predicted)
Flash Point	139°C
Vapor Presure	0.00124mmHg at 25°C
pKa	12.41±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.598

1H-imidazole-2-carboxaldehyde, 4-methyl- - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves.
WGK Germany	3
Hazard Class	IRRITANT

1H-imidazole-2-carboxaldehyde, 4-methyl- - Introduction

4-Methyl-1H-imidazole-2-carbaldehyde is an organic compound with the formula C5H6N2O. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: 4-methyl -1H-imidazole-2-carbaldehyde is a colorless to light yellow liquid.
-Solubility: It can be dissolved in water and organic solvents.
-Melting point: approximately -7°C.
-Boiling point: about 155°C.

Use:
-Industrial use: 4-Methyl-1H-imidazole-2-formaldehyde can be used as a catalyst, enzyme inhibitor and intermediate, and is widely used in organic synthesis reactions.
-Medical use: It is widely used in the field of drug research, such as as a precursor of anti-tumor drugs.

Method:
4-Methyl -1H-imidazole-2-carbaldehyde can be synthesized by the following steps:
1. methylamine and formaldehyde are reacted under acidic conditions to generate N-methyl formaldehyde amine.
2. reacting N-methyl formaldehyde amine with a solution containing carbon tetrachloride and cuprous chloride (CuCl2) to generate 4-methyl -1H-imidazole-2-formaldehyde.

Safety Information:
-4-methyl -1H-imidazole-2-formaldehyde is irritating and should be careful to avoid contact with skin and eyes.
-Wear appropriate personal protective equipment, such as gloves and goggles, during use or operation.
-When storing, keep it in a closed container, away from fire and oxidizing agents.
-When handling 4-methyl-1H-imidazole-2-formaldehyde, pay attention to proper ventilation and follow relevant safety procedures.

Last Update：2024-04-09 02:00:41