1H-pyrrole-1-undecanoic acid, 2,5-dihydro-2,5-dioxo-
11-Maleimidoundecanoic acid
CAS: 57079-01-3
Molecular Formula: C15H23NO4
1H-pyrrole-1-undecanoic acid, 2,5-dihydro-2,5-dioxo- - Names and Identifiers
| Name | 11-Maleimidoundecanoic acid |
| Synonyms | Mal-(CH2)10-COOH (KMUA) Maleimidoundecanoic acid 11-Maleimidoundecanoic acid 11-Maleimide undecanoic acid N-(10-Carboxydecyl)MaleiMide N-κ-MaleiMidoundecanoic acid(KMUA) 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-undecanoic Acid 1H-pyrrole-1-undecanoic acid, 2,5-dihydro-2,5-dioxo- 11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoic acid |
| CAS | 57079-01-3 |
| InChI | InChI=1/C15H23NO4/c17-13-10-11-14(18)16(13)12-8-6-4-2-1-3-5-7-9-15(19)20/h10-11H,1-9,12H2,(H,19,20) |
1H-pyrrole-1-undecanoic acid, 2,5-dihydro-2,5-dioxo- - Physico-chemical Properties
| Molecular Formula | C15H23NO4 |
| Molar Mass | 281.35 |
| Density | 1.139±0.06 g/cm3(Predicted) |
| Melting Point | 89-90°C |
| Boling Point | 452.8±18.0 °C(Predicted) |
| Flash Point | 227.6°C |
| Solubility | Soluble in methanol, and chloroform. |
| Vapor Presure | 1.86E-09mmHg at 25°C |
| Appearance | Powder |
| Color | White to off-white |
| pKa | 4.78±0.10(Predicted) |
| Storage Condition | -20°C Freezer |
| Refractive Index | 1.515 |
| MDL | MFCD00941279 |
1H-pyrrole-1-undecanoic acid, 2,5-dihydro-2,5-dioxo- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
1H-pyrrole-1-undecanoic acid, 2,5-dihydro-2,5-dioxo- - Introduction
11-Maleimidoundecanoic acid(11-Maleimidoundecanoic acid) is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 11-Maleimidoundecanoic acid is a colorless solid.
-Solubility: It has good solubility in some organic solvents (such as dimethyl sulfoxide, dimethylformamide, etc.).
-Melting point: Its melting point is about 140-145 degrees Celsius.
Use:
-Biochemical research: 11-Maleimidoundecanoic acid is usually used as a biomarker reagent to react with thiol compounds (such as cysteine residues) to label proteins and nanoparticles.
-Drug development: Because of its structural activity of the key maleamide group, the compound is used in the study of drug delivery systems and drug molecular modification.
Preparation Method:
The method for preparing 11-Maleimidoundecanoic acid is usually obtained by reacting maleoyl chloride with undecylamine. The specific procedure is generally to add maleoyl chloride to the solution of undecylamine, and after a period of reaction, the target product is obtained by crystallization or extraction purification.
Safety Information:
- 11-Maleimidoundecanoic acid is generally safe under correct use and handling. However, it is a chemical and should follow appropriate laboratory safety practices.
-The compound is irritating to the eyes and skin, so direct contact must be avoided. Wear protective glasses and gloves during operation.
-Should be stored in a dry, cool place and avoid contact with incompatible substances such as oxidants.
Please note: The above information is for reference only. When using or handling this compound, please always refer to the detailed safety data sheet and operating instructions provided by the relevant chemical supplier.
Nature:
-Appearance: 11-Maleimidoundecanoic acid is a colorless solid.
-Solubility: It has good solubility in some organic solvents (such as dimethyl sulfoxide, dimethylformamide, etc.).
-Melting point: Its melting point is about 140-145 degrees Celsius.
Use:
-Biochemical research: 11-Maleimidoundecanoic acid is usually used as a biomarker reagent to react with thiol compounds (such as cysteine residues) to label proteins and nanoparticles.
-Drug development: Because of its structural activity of the key maleamide group, the compound is used in the study of drug delivery systems and drug molecular modification.
Preparation Method:
The method for preparing 11-Maleimidoundecanoic acid is usually obtained by reacting maleoyl chloride with undecylamine. The specific procedure is generally to add maleoyl chloride to the solution of undecylamine, and after a period of reaction, the target product is obtained by crystallization or extraction purification.
Safety Information:
- 11-Maleimidoundecanoic acid is generally safe under correct use and handling. However, it is a chemical and should follow appropriate laboratory safety practices.
-The compound is irritating to the eyes and skin, so direct contact must be avoided. Wear protective glasses and gloves during operation.
-Should be stored in a dry, cool place and avoid contact with incompatible substances such as oxidants.
Please note: The above information is for reference only. When using or handling this compound, please always refer to the detailed safety data sheet and operating instructions provided by the relevant chemical supplier.
Last Update：2024-04-09 20:49:11
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