2 - chloro - 4 - broMide pyridine
2-Chloro-4-bromopyridine
CAS: 73583-37-6
Molecular Formula: C5H3BrClN
2 - chloro - 4 - broMide pyridine - Names and Identifiers
| Name | 2-Chloro-4-bromopyridine |
| Synonyms | 2-CHLORO-4-F 2-chloro-4-bromopyridne 4-BROMO-2-CHLOROPYRIDINE 2-CHLORO-4-FLUOROYRIDINE 2-Chloro-4-bromopyridine 2-Chloro-4-boroMopyridine PYRIDINE, 4-BROMO-2-CHLORO- 2 - chloro - 4 - broMide pyridine |
| CAS | 73583-37-6 |
| EINECS | 629-180-4 |
| InChI | InChI=1/C5H3BrClN/c6-4-1-2-8-5(7)3-4/h1-3H |
2 - chloro - 4 - broMide pyridine - Physico-chemical Properties
| Molecular Formula | C5H3BrClN |
| Molar Mass | 192.44 |
| Density | 1.7336g/mLat 25°C(lit.) |
| Melting Point | 27 C |
| Boling Point | 70 °C / 3mmHg |
| Flash Point | 225°F |
| Water Solubility | Not miscible or difficult to mix in water. |
| Vapor Presure | 0.122mmHg at 25°C |
| Appearance | White-like crystal |
| Specific Gravity | 1.7336 |
| Color | Yellow |
| pKa | 0.24±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | n20/D 1.5900(lit.) |
| MDL | MFCD03840756 |
2 - chloro - 4 - broMide pyridine - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Class | IRRITANT |
2 - chloro - 4 - broMide pyridine - Reference Information
| overview | 2-chloro-4-bromopyridine is a class of pyridine compounds, mainly used as intermediates in organic synthesis. |
| Use | 2-chloro-4-bromopyridine is an organic synthesis intermediate. It is mainly used to synthesize 3-[[4-(2-methoxyphenyl)-2-pyridyl] amino]-benzesulfonamide, which is an effective CDK9 inhibitor in the treatment of midline cancer. It can also be used to prepare (pyrimidine amino) benzamide derivatives with anticancer activity as hedgehog signaling pathway inhibitors. |
Last Update：2024-04-09 15:16:36
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