ChemBK
  • Home
  • Product Category

2,4,5-Trimethoxybenzaldehyde

2,4,5-Trimethoxybenzaldehyde

CAS: 4460-86-0

Molecular Formula: C10H12O4

  1. Home
  2. Product Category
  3. Organic raw materials
  4. Aldehydes
  5. 2,4,5-Trimethoxybenzaldehyde

2,4,5-Trimethoxybenzaldehyde - Names and Identifiers

Name 2,4,5-Trimethoxybenzaldehyde
Synonyms Gazarin
NCI-C61632
ASARALDEHYDE
ASARONALDEHYDE
Asarylaldehyde
Azarylaldehyde
2,4,5-trimethyl ether
2,4,5-TRIMETHOXYBENZALDEHYDE
2,4,5-Trimethoxybenzaldehyde
CAS 4460-86-0
EINECS 224-713-3
InChI InChI=1/C10H12O4/c1-12-8-5-10(14-3)9(13-2)4-7(8)6-11/h4-6H,1-3H3
InChIKey IAJBQAYHSQIQRE-UHFFFAOYSA-N

2,4,5-Trimethoxybenzaldehyde - Physico-chemical Properties

Molecular FormulaC10H12O4
Molar Mass196.2
Density1.2166 (rough estimate)
Melting Point112-114 °C (lit.)
Boling Point140°C 4mm
Flash Point140°C/4mm subl.
Water Solubility<0.1 g/100 mL at 22 ºC
Solubility Water solubility <0.1g/100 mL (22°C)
Vapor Presure0.000125mmHg at 25°C
AppearanceWhite-like crystal
ColorWhite to light beige
BRN1951403
Storage ConditionKeep in dark place,Sealed in dry,Room Temperature
SensitiveAir Sensitive
Refractive Index1.5550 (estimate)
MDLMFCD00003312
Physical and Chemical PropertiesOff-white crystals. Melting point 109-112 °c.
UseUsed as a pharmaceutical intermediate for the preparation of asarone
In vitro studyAsaraldehyde production is abundant, but not at all in its liquid medium as well as in its natural host, C. kanehirae wood. If cultured with acid-digested sawdust or vanillin from C. kanehirae wood, Asaraldehyde was produced in its medium. 100 mg/ml Asaraldehyde showed 3.32% prostaglandin H endoperoxide synthase -1 (COX-1) inhibitory activity, 52.69% of prostaglandin H endoperoxide synthase -2 (COX-2) inhibitory activity. 100 µg/mL of Asaraldehyde tended to inhibit the COX-2 enzyme. The inhibition ratio of Asaraldehyde to COX-2/COX-1 was 17.68 at 100 µg/mL compared to control. Asaraldehyde down-regulates the expression of C/EBPβ, C/ebpδ and C/EBPα, and inhibits the expression of PPARγ1, PPARγ2 and acetyl-coenzyme A carboxylase (ACC).

2,4,5-Trimethoxybenzaldehyde - Risk and Safety

Hazard SymbolsC - Corrosive
Corrosive
Risk CodesR36/37/38 - Irritating to eyes, respiratory system and skin.
R34 - Causes burns
Safety DescriptionS22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S27 - Take off immediately all contaminated clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany3
RTECSCU8460000
TSCAYes
HS Code29124990

2,4,5-Trimethoxybenzaldehyde - Upstream Downstream Industry

Raw Materials1,4-Benzoquinone

2,4,5-Trimethoxybenzaldehyde - Reference

Reference
Show more
1. Dong Xiaoke, Liu Jinmin, Li Zhonghao, Yuan Siyuan, Wang Kaiyue, Li Lili, Zheng xiangchun. Study on the main blood components and pharmacokinetics of chaibei Zhixian decoction in rats [J]. Global Journal of Traditional Chinese Medicine, 2021,14(03):377-383.

2,4,5-Trimethoxybenzaldehyde - Reference Information

NIST chemical information Information provided by: webbook.nist.gov (external link)
EPA chemical information Information provided by: ofmpub.epa.gov (external link)
overview 2,4, 5-trimethoxybenzaldehyde is mainly used to prepare asarone. Alpha-asarone mainly exists in the volatile oil of natural products such as Acorus calamus. It has sedative, hypnotic and antibacterial effects. It is clinically used for the treatment of chronic bronchitis, epilepsy, coma and other mental diseases. Since the 1960s, the extraction, synthesis, pharmacology, toxicology and clinic of α-asarone monomer, an effective component of Acorus plants, have been extensively studied at home and abroad, and significant progress has been made.
biological activity Asaraldehyde (Asaronaldehyde) is a natural COX-2 inhibitor, which is 17 times more selective than COX-1.
TargetValue
use used for content determination/identification/pharmacological experiments, etc.
Used as a pharmaceutical intermediate to prepare asarone
toxic substance data information provided by: pubchem.ncbi.nlm.nih.gov (external link)
Last Update：2024-04-09 20:52:54
2,4,5-Trimethoxybenzaldehyde
Supplier List
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: 2,4,5-Trimethoxybenzaldehyde Request for quotation
CAS: 4460-86-0
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hubei Longxin Chemical Industry Co., Ltd
Spot supply
Product Name: 2,4,5-Trimethoxybenzaldehyde Request for quotation
CAS: 4460-86-0
Tel: 15335994747
Email: 3521670276@qq.com
Mobile: 15335994747
QQ: 3521670276 Click to send a QQ message
Wechat: A2020071098
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: 2,4,5-Trimethoxybenzaldehyde Request for quotation
CAS: 4460-86-0
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: 2,4,5-Trimethoxybenzaldehyde Visit Supplier Webpage Request for quotation
CAS: 4460-86-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
Shanghai Worldyang Chemical Co.,Ltd.
Product Name: 2,4,5-Trimethoxybenzaldehyde Request for quotation
CAS: 4460-86-0
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228 Click to send a QQ message
Wechat: 13651600618
WhatsApp: +8613651600618
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: 2,4,5-Trimethoxybenzaldehyde Request for quotation
CAS: 4460-86-0
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hubei Longxin Chemical Industry Co., Ltd
Spot supply
Product Name: 2,4,5-Trimethoxybenzaldehyde Request for quotation
CAS: 4460-86-0
Tel: 15335994747
Email: 3521670276@qq.com
Mobile: 15335994747
QQ: 3521670276 Click to send a QQ message
Wechat: A2020071098
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: 2,4,5-Trimethoxybenzaldehyde Request for quotation
CAS: 4460-86-0
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: 2,4,5-Trimethoxybenzaldehyde Visit Supplier Webpage Request for quotation
CAS: 4460-86-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
Shanghai Worldyang Chemical Co.,Ltd.
Product Name: 2,4,5-Trimethoxybenzaldehyde Request for quotation
CAS: 4460-86-0
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228 Click to send a QQ message
Wechat: 13651600618
WhatsApp: +8613651600618
View History
2,4,5-Trimethoxybenzaldehyde
Raw Materials for 2,4,5-Trimethoxybenzaldehyde
1,4-Benzoquinone
  • Home
  • Product Category

© 2015, 2023 ChemBK.com All Rights Reserved | Build: 20230617001