2,6-二巯基嘌呤
2,6-Dithiopurine
CAS: 5437-25-2
Molecular Formula: C5H4N4S2
2,6-二巯基嘌呤 - Names and Identifiers
| Name | 2,6-Dithiopurine |
| Synonyms | DITHIOXANTHINE 2,6-THIOPURINE 2,6-DITHIOPURINE 2,6-Dithiopurine 2,6-PURINEDITHIOL 2,6-DITHIOXANTHINE 2,6-DIMERCAPTOPURINE 2,6-dimercaptopurine 9H-PURINE-2,6-DITHIOL 3,7-dihydro-1H-purine-2,6-dithione 3,5-dihydro-1H-purine-2,6-dithione 6-thioxo-6,7-dihydro-3H-purine-2-thiolate |
| CAS | 5437-25-2 |
| EINECS | 226-608-8 |
| InChI | InChI=1/C5H4N4S2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)/p-1 |
2,6-二巯基嘌呤 - Physico-chemical Properties
| Molecular Formula | C5H4N4S2 |
| Molar Mass | 184.24 |
| Density | 1.541 (estimate) |
| Melting Point | >350°C(lit.) |
| Boling Point | 496.2±37.0 °C(Predicted) |
| Flash Point | 255.1°C |
| Water Solubility | slightly soluble |
| Solubility | slightly soluble |
| Vapor Presure | 4.65E-10mmHg at 25°C |
| Appearance | Powder |
| Color | Pale yellow |
| pKa | 6.77±0.20(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.5605 (estimate) |
| MDL | MFCD00022644 |
2,6-二巯基嘌呤 - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| RTECS | UO8475000 |
| HS Code | 29335990 |
2,6-二巯基嘌呤 - Introduction
2,6-Dithiopurine(2,6-Dithiopurine) is an organic compound with the chemical formula C5H4N4S2. It is a purine compound with two sulfur atoms and one nitrogen atom. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 2,6-Dithiopurine is a yellow powdery solid.
-Solubility: It is insoluble in water, but can be dissolved in some organic solvents, such as methanol and dimethyl sulfoxide.
Use:
-Research purposes: 2,6-Dithiopurine is commonly used in organic synthesis reactions and catalytic reactions in scientific research. It can be used as a catalyst or ligand to participate in various organic conversion reactions, such as C- C bond formation.
Preparation Method:
The preparation of 2,6-Dithiopurine usually involves the following steps:
1. Synthesis of purine: Purine is synthesized by specific organic synthesis reaction.
2. Differential thiolation: The sulfur atom in the purine substance is protected using a thiol reagent.
3. Thiol deprotection: The protecting group is removed by appropriate reaction conditions to give 2,6-Dithiopurine.
Safety Information:
2,6-Dithiopurine needs to pay attention to the following safety matters in laboratory operation:
-Take care to avoid inhalation, contact with skin and ingestion of this compound.
-Wear appropriate protective equipment such as gloves, glasses and laboratory goggles when performing the operation.
-Operate under a closed ventilation system to avoid inhaling toxic gases.
-Storage should be placed in a dry, cool place, away from heat and fire.
-Comply with laboratory safety procedures and relevant regulations.
Nature:
-Appearance: 2,6-Dithiopurine is a yellow powdery solid.
-Solubility: It is insoluble in water, but can be dissolved in some organic solvents, such as methanol and dimethyl sulfoxide.
Use:
-Research purposes: 2,6-Dithiopurine is commonly used in organic synthesis reactions and catalytic reactions in scientific research. It can be used as a catalyst or ligand to participate in various organic conversion reactions, such as C- C bond formation.
Preparation Method:
The preparation of 2,6-Dithiopurine usually involves the following steps:
1. Synthesis of purine: Purine is synthesized by specific organic synthesis reaction.
2. Differential thiolation: The sulfur atom in the purine substance is protected using a thiol reagent.
3. Thiol deprotection: The protecting group is removed by appropriate reaction conditions to give 2,6-Dithiopurine.
Safety Information:
2,6-Dithiopurine needs to pay attention to the following safety matters in laboratory operation:
-Take care to avoid inhalation, contact with skin and ingestion of this compound.
-Wear appropriate protective equipment such as gloves, glasses and laboratory goggles when performing the operation.
-Operate under a closed ventilation system to avoid inhaling toxic gases.
-Storage should be placed in a dry, cool place, away from heat and fire.
-Comply with laboratory safety procedures and relevant regulations.
Last Update：2024-04-10 22:29:15
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View History
2,6-二巯基嘌呤
邻氟苯酸2—氟苯甲酸
1-甲基-2-丙烯基氯化镁 溶液
6-甲基哌啶-3-甲酸甲酯盐酸盐
氯苯甲嗪相关物质B
SODIUM PRASTERONR SULFATE
3-甲基丁酸乙酯(异戊酸乙酯)
(±)-1H-苯并咪唑-7-羧酸-2-乙氧基-1-[[2-(1H-四氮-5-基)[1,1-二苯]-4-基]甲基]-1-[[(环己基氧基)羰基]氧基]乙酯
溴化 1-甲基-3-羟基吡啶鎓二甲氨基甲酸酯
2-甲硫基-4-氨基-5-嘧啶甲酸乙酯
邻氟苯酸2—氟苯甲酸
1-甲基-2-丙烯基氯化镁 溶液
6-甲基哌啶-3-甲酸甲酯盐酸盐
氯苯甲嗪相关物质B
SODIUM PRASTERONR SULFATE
3-甲基丁酸乙酯(异戊酸乙酯)
(±)-1H-苯并咪唑-7-羧酸-2-乙氧基-1-[[2-(1H-四氮-5-基)[1,1-二苯]-4-基]甲基]-1-[[(环己基氧基)羰基]氧基]乙酯
溴化 1-甲基-3-羟基吡啶鎓二甲氨基甲酸酯
2-甲硫基-4-氨基-5-嘧啶甲酸乙酯