2'-Amino-2'-Deoxyguanosine
2'-Amino-2'-deoxyguanosine
CAS: 60966-26-9
Molecular Formula: C10H14N6O4
2'-Amino-2'-Deoxyguanosine - Names and Identifiers
| Name | 2'-Amino-2'-deoxyguanosine |
| Synonyms | 2AG NSC 241514 2'-NH2-2-NH2-dA 2''-AMINO-D-GUANOSINE 2'-Deoxy-2'-aminoguanosine 2'-Amino-2'-deoxyguanosine 2'-AMINO-2'-DEOXY-GUANOSINE Guanosine, 2'-amino-2'-deoxy- 2'-Amino-2'-deoxy-D-guanosine 2'-Amino-2,6-diaminopurine 2'-deoxyriboside 9-(2-Amino-2-deoxy-β-D-ribofuranosyl)-guanine 2''-AMINO-2''-DEOXYGUANOSINE (2''-DEOXY-2''-AMINOGUANOSINE) 2-amino-9-(2-amino-2-deoxypentofuranosyl)-3,9-dihydro-6H-purin-6-one |
| CAS | 60966-26-9 |
| EINECS | 1308068-626-2 |
| InChI | InChI=1/C10H14N6O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1,11H2,(H3,12,14,15,19) |
2'-Amino-2'-Deoxyguanosine - Physico-chemical Properties
| Molecular Formula | C10H14N6O4 |
| Molar Mass | 282.26 |
| Density | 2.25±0.1 g/cm3(Predicted) |
| Melting Point | 252-254 °C |
| Boling Point | 753.4°C at 760 mmHg |
| Flash Point | 409.4°C |
| Solubility | DMSO (Slightly, Heated), Water (Slightly, Heated) |
| Vapor Presure | 7.53E-24mmHg at 25°C |
| Appearance | Powder |
| Color | White to Off-white |
| pKa | 9?+-.0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.985 |
| MDL | MFCD01723954 |
2'-Amino-2'-Deoxyguanosine - Risk and Safety
| RTECS | MF8752000 |
2'-Amino-2'-Deoxyguanosine - Introduction
2 '-Amino-2'-deoxyguanosine is a nucleoside compound, which is formed by replacing a hydroxyl group with an amino group on the 2 'carbon of guanosine. It has a chemical formula of C10H14N5O4 and a molecular weight of 282.25g/mol.
2 '-Amino-2'-deoxyguanosine has many important properties and uses. First of all, it is one of the components of DNA and RNA. It can be used as one of the bases in nucleic acids and plays an important function in organisms. Secondly, it has important application value for studying the structure, function and interaction of nucleic acids. In addition, it can also be used in the preparation of DNA fluorescent probes, nucleic acid modification and synthetic drugs.
Methods for preparing 2 '-Amino-2'-deoxyguanosine are generally by chemical synthesis. Specifically, starting from guanosine, the hydroxyl group at the 2 '-position can be converted into an amino group by a series of chemical reactions.
Regarding safety information, since 2 '-Amino-2'-deoxyguanosine is a chemical substance, it is necessary to pay attention to safety measures when using and handling, avoid contact with skin and inhalation of its dust or gas. In addition, the toxicity and carcinogenicity of this compound need further study. Therefore, it is necessary to follow the relevant laboratory practices and protect your health through appropriate personal protective measures.
2 '-Amino-2'-deoxyguanosine has many important properties and uses. First of all, it is one of the components of DNA and RNA. It can be used as one of the bases in nucleic acids and plays an important function in organisms. Secondly, it has important application value for studying the structure, function and interaction of nucleic acids. In addition, it can also be used in the preparation of DNA fluorescent probes, nucleic acid modification and synthetic drugs.
Methods for preparing 2 '-Amino-2'-deoxyguanosine are generally by chemical synthesis. Specifically, starting from guanosine, the hydroxyl group at the 2 '-position can be converted into an amino group by a series of chemical reactions.
Regarding safety information, since 2 '-Amino-2'-deoxyguanosine is a chemical substance, it is necessary to pay attention to safety measures when using and handling, avoid contact with skin and inhalation of its dust or gas. In addition, the toxicity and carcinogenicity of this compound need further study. Therefore, it is necessary to follow the relevant laboratory practices and protect your health through appropriate personal protective measures.
Last Update：2024-04-09 21:01:54
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