Name | 2'-O-Methylkurarinone |
Synonyms | 2'-O-Methylkurarinone (2S)-2-Methoxykurarinone Kurarinone, 2'-O-methyl- (2S)-2-METHOXYKURARINONE (2S)-7-hydroxy-2-(4-hydroxy-2-methoxyphenyl)-5-methoxy-8-[(2R)-5-methyl-2-prop-1-en-2-ylhex-4-enyl]-2,3-dihydrochromen-4-one 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxy-2-methoxyphenyl)-5-methoxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2S)- |
CAS | 270249-38-2 |
Molecular Formula | C27H32O6 |
Molar Mass | 452.54 |
Density | 1.171±0.06 g/cm3(Predicted) |
Melting Point | 112-115℃ |
Boling Point | 643.6±55.0 °C(Predicted) |
pKa | 7.50±0.40(Predicted) |
Storage Condition | 2-8°C |
Plant Source: | Sophora flavescens |
biological activity | (2S)-2 '-Methoxykurarinone is a compound isolated from the root of Sophora flavescens Ait, it has anti-inflammatory, antipyretic, anti-diabetic and anti-tumor effects. (2S)-2 '-Methoxykurarinone inhibits osteoclast formation and bone resorption by down-regulating RANKL signaling. (2S)-2 '-Methoxykurarinone has cytotoxic activity against human myeloid leukemia HL-60 cells. |