2(1H)-Azulenone, 4,5,6,7,8,8a-hexahydro-6-hydroxy-5-(1-hydroxy-1-methylethyl)-3,8-dimethyl-, (5S,6R,8S,8aR)- - Names and Identifiers
Name | Torilolone
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Synonyms | Torilolone 8beta,11-Dihydroxy-1beta-guai-4-en-3-one 2(1H)-Azulenone, 4,5,6,7,8,8a-hexahydro-6-hydroxy-5-(1-hydroxy-1-methylethyl)-3,8-dimethyl-, (5S,6R,8S,8aR)-
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CAS | 13018-09-2
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2(1H)-Azulenone, 4,5,6,7,8,8a-hexahydro-6-hydroxy-5-(1-hydroxy-1-methylethyl)-3,8-dimethyl-, (5S,6R,8S,8aR)- - Physico-chemical Properties
Molecular Formula | C15H24O3
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Molar Mass | 252.35 |
Density | 1.11±0.1 g/cm3(Predicted) |
Melting Point | 179-180℃ |
Boling Point | 402.0±45.0 °C(Predicted) |
Appearance | Crystal |
pKa | 14.86±0.70(Predicted) |
Storage Condition | 2-8℃ |
2(1H)-Azulenone, 4,5,6,7,8,8a-hexahydro-6-hydroxy-5-(1-hydroxy-1-methylethyl)-3,8-dimethyl-, (5S,6R,8S,8aR)- - Introduction
Torilolone is a synthetic cisplatin compound with anti-tumor activity. Here are details about Toliloron:
Properties: Toliloron is a white crystalline powder, soluble in organic solvents such as dichloromethane, methanol and ethanol. It is a strong metal ion chelating agent that forms stable complexes with metal ions such as platinum, copper and iron ions.
Purpose: Toliloron is mainly used as an anti-tumor drug, which can inhibit the proliferation of tumor cells and induce apoptosis of tumor cells in chemotherapy. It also has anti-inflammatory, antibacterial and antifungal activity and can be used to treat some skin infections.
preparation method: the synthesis method of tolilon is more complex, generally including multi-step reaction. The method for preparing tolilolone includes substitution reaction, reduction reaction, Metal complexation reaction and deprotection reaction of brominated peptide.
Safety information: When using Toliloron, you need to pay attention to the following safety information:
1. Toliloron can only be used in qualified laboratories or medical institutions.
2. Use must wear personal protective equipment, such as gloves, protective glasses and laboratory coat.
3. Avoid contact with skin and eyes, and maintain good ventilation.
4. Avoid inhalation of powder or solution, such as accidentally inhaled or taken by mistake, should immediately seek medical attention.
5. Follow local waste disposal regulations when handling waste.
6. In the use or storage of Tolilon, avoid mixing with other chemicals to prevent unsafe reactions.
Please note that the above information is for reference only. When using Toliloron, follow the relevant instructions and safety precautions for specific products.
Last Update:2024-04-09 21:21:28