2(1H)-Pyridinone, 3-amino-4-methyl-

2(1H)-Pyridinone, 3-amino-4-methyl- - Names and Identifiers

Name	3-Amino-4-methyl-2(1H)-pyridinone
Synonyms	3-AMINO-2-HYDROXY-4-PICOLINE 3-Amino-4-methylpyridin-2(1H)-one 3-Amino-4-methyl-1H-pyridin-2-one 3-Amino-4-methyl-2(1H)-pyridinone 2-hydroxy-4-methyl-3-aminopyridine 2(1H)-Pyridinone, 3-amino-4-methyl-
CAS	33252-54-9
InChI	InChI=1S/C6H8N2O/c1-4-2-3-8-6(9)5(4)7/h2-3H,7H2,1H3,(H,8,9)

2(1H)-Pyridinone, 3-amino-4-methyl- - Physico-chemical Properties

Molecular Formula	C6H8N2O
Molar Mass	124.14
Density	1.137±0.06 g/cm3(Predicted)
Boling Point	336.2±35.0 °C(Predicted)
pKa	13.90±0.10(Predicted)
Storage Condition	2-8°C

2(1H)-Pyridinone, 3-amino-4-methyl- - Introduction

3-Amino-4-methyl-2(1H)-pyridinone, also known as 3-Amino-4-methyl-2(1H)-pyridinone, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: 3-Amino-4-methyl-2(1H)-pyridinone exists in the form of white or light yellow crystals or crystalline powder.
-Melting point: Its melting point is about 150-152 ° C.
-Solubility: 3-Amino-4-methyl-2(1H)-pyridinone can be dissolved in water and some organic solvents (such as alcohols and ketones).

Use:
-Chemical synthesis: 3-Amino-4-methyl-2(1H)-pyridinone is an important organic synthesis intermediate, which is widely used in the manufacture of medicines and pesticides. It can be used as a starting material for the synthesis of a variety of biologically active compounds, including some antitumor and antiviral drugs.

Method:
A common preparation method is to obtain 3-Amino-4-methyl-2(1H)-pyridinone by reacting pyridine -2, 3-dione and methylamine under alkaline conditions. The specific reaction process is as follows:
1. Mix the pyridine-2, 3-dione with methylamine.
2. Under the action of basic catalyst, the reaction mixture is heated.
3. The product was filtered and purified by crystallization.

Safety Information:
3-Amino-4-methyl-2(1H)-pyridinone is generally considered to be relatively safe under normal conditions of use. However, as an organic compound, it should comply with general laboratory safety practices. It is recommended to wear appropriate personal protective equipment, such as laboratory gloves and protective glasses, when exposed to this compound. Avoid prolonged inhalation of its dust or contact with skin and eyes. If ingested accidentally or inhaled by mistake, seek medical attention promptly.

Last Update：2024-04-09 20:45:29