2,2'-二吡啶甲基胺
Dipicolylamine
CAS: 1539-42-0
Molecular Formula: C12H13N3
2,2'-二吡啶甲基胺 - Names and Identifiers
| Name | Dipicolylamine |
| Synonyms | Dipicolylamine 2-Pyridinemethanamine Bis-pyridin-2-ylmethyl-amine Bis(pyridine-2-ylmethyl)amine 2,2'-Iminobismethylenebispyridine 2,2''-(IMINODIMETHYLENE)DI- PYRIDINE N-(2-Pyridinylmethyl)-2-pyridinemethanamine 2-PyridineMethanaMine, N-(2-pyridinylMethyl)- |
| CAS | 1539-42-0 |
| EINECS | 216-266-8 |
| InChI | InChI=1/C12H13N3/c1-3-7-14-11(5-1)9-13-10-12-6-2-4-8-15-12/h1-8,13H,9-10H2 |
| InChIKey | KXZQYLBVMZGIKC-UHFFFAOYSA-N |
2,2'-二吡啶甲基胺 - Physico-chemical Properties
| Molecular Formula | C12H13N3 |
| Molar Mass | 199.25 |
| Density | 1.107 g/mL at 25 °C (lit.) |
| Boling Point | 139-141 °C/1 mmHg (lit.) |
| Flash Point | >230°F |
| Solubility | water: soluble (partially miscible)(lit.) |
| Vapor Presure | 0.000284mmHg at 25°C |
| Appearance | clear liquid |
| Color | White to Yellow to Green |
| pKa | 5.89±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | n20/D 1.578(lit.) |
2,2'-二吡啶甲基胺 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29333990 |
2,2'-二吡啶甲基胺 - Reference Information
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Use | dimethylpyridinamine is a heterocyclic organic compound and can be used as a pharmaceutical intermediate. |
| preparation | add 2-aldopyridine (10mmol) in a ML three-necked flask, 20ml of a methanol solution of 2-aminomethylpyridine (10mmol) was added dropwise to 2-aldypyridine, and the mixture was stirred at room temperature for 10h after completion of the dropwise addition. NaBH4(20mmol) was slowly added to the reaction system, and the reaction solution changed from brown to light yellow. After stirring overnight at room temperature, the solvent was evaporated under reduced pressure, and then 20ml of distilled water was added, the pH was adjusted to Neutral with 32% dilute hydrochloric acid under stirring, and the mixture was extracted with dichloromethane (3 × 30ml). The lower yellow solution was collected, dried over anhydrous MgSO4, and distilled under reduced pressure to obtain a yellow liquid in 95% yield. |
Last Update：2024-04-09 20:52:54
