2,2,3,3-D4-3-(TRIMETHYLSILYL)PROPIONIC ACID SODIUM SALT - Names and Identifiers
Name | 2,2,3,3,-d(4)-3-Trimethylsilyl)propionic acid sodium salt
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Synonyms | TMSP-2,2,3,3-D4 SODIUM 2,2,3,3-D4 3-TRIMETHYLSILYLPROPIONATE 3-(TRIMETHYLSILYL)PROPIONIC ACID-D4 SODIUM SALT 3-(TRIMETHYLSILYL)PROPIONIC ACID SODIUM SALT-D4 2,2,3,3-D4-3-(TRIMETHYLSILYL)PROPIONIC ACID SODIUM SALT 3-(TRIMETHYLSILYL)PROPIONIC-2,2,3,3-D4 ACID, SODIUM SALT 2,2,3,3,-d(4)-3-Trimethylsilyl)propionic acid sodium salt 3-(TRIMETHYLSILYL)-TETRADEUTERO PROPIONIC ACID SODIUM SALT 2,2,3,3-TETRADEUTERO-3(TRIMETHYLSILYL)-PROPIONIC ACID SODIUM SALT
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CAS | 24493-21-8
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EINECS | 246-286-2 |
InChI | InChI=1/C6H14O2Si.Na/c1-9(2,3)5-4-6(7)8;/h4-5H2,1-3H3,(H,7,8);/q;+1/p-1/i4D2,5D2 |
2,2,3,3-D4-3-(TRIMETHYLSILYL)PROPIONIC ACID SODIUM SALT - Physico-chemical Properties
Molecular Formula | C6H15NaO2Si
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Molar Mass | 170.26 |
Melting Point | 300°C |
Boling Point | 223.6°C at 760 mmHg |
Flash Point | 89°C |
Water Solubility | Soluble in water. |
Solubility | Methanol (Slightly), Water (Slightly) |
Vapor Presure | 0.0351mmHg at 25°C |
Appearance | Powder |
Color | White |
BRN | 4046239 |
PH | 7.0-9.0 (1% in solution) |
Storage Condition | Store below +30°C. |
Sensitive | Hygroscopic |
MDL | MFCD00002762 |
2,2,3,3-D4-3-(TRIMETHYLSILYL)PROPIONIC ACID SODIUM SALT - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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WGK Germany | 3 |
HS Code | 28459000 |
2,2,3,3-D4-3-(TRIMETHYLSILYL)PROPIONIC ACID SODIUM SALT - Introduction
2,2,3,3,-d(4)-3-Trimethylsilyl)propionic acid sodium salt is an organic compound with the chemical formula C8H12D4NaO2Si. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2,2,3,3,-d(4)-3-Trimethylsilyl)propionic acid sodium salt is a white crystalline solid.
-Solubility: It is soluble in water and also soluble in organic solvents such as alcohols and ethers.
-preservation conditions: should be stored in a dry, cool place, avoid direct sunlight.
Use:
-as NMR standard: 2,2,3,3,-d(4)-3-Trimethylsilyl)propionic acid sodium salt is often used as an internal standard for nuclear magnetic resonance (NMR) analysis, used to correct for chemical shifts in deuterium spectra.
-for Organic Synthesis: it can be used as a basic reagent in organic synthesis, involved in esterification, acylation and other reactions.
Method:
2,2,3,3,-d(4)-3-Trimethylsilyl)propionic acid sodium salt is generally synthesized by the following steps:
1.3-(trimethylsilyl) propionic acid (3-Trimethylsilylpropionic acid) is reacted with D2O to generate 2,2,3,3-d(4)-3-(trimethylsilyl) propionic acid. A diazonium salt, such as ethanoborate (beta-trifluoromethyl diazo)ethyl ester, is used in the reaction to promote the exchange of deuterium (D) and silicon (Si).
2. The product of the reaction reacts with an alkaline solution such as sodium hydroxide (NaOH) to form 2,2,3,3,-d(4)-3-Trimethylsilyl)propionic acid sodium salt.
Safety Information:
The specific safety evaluation of
2,2,3,3,-d(4)-3-Trimethylsilyl)propionic acid sodium salt has not been clearly reported. However, according to the general overview of similar compounds, it may have a toxic effect on the environment. When using and handling, should follow the regular laboratory safety procedures, avoid contact with skin, eyes and inhalation. For accidental contact or ingestion, seek medical help promptly.
Last Update:2024-04-10 22:29:15