2,2-difluoro-2-(4-(trifluoromethoxy)phenyl)acetic acid - Names and Identifiers
2,2-difluoro-2-(4-(trifluoromethoxy)phenyl)acetic acid - Introduction
2,2-difluoro-2-(4-(trifluoromethoxy)phenyl)acetic acid is an organic compound with the chemical formula C10H5F5O3.
Its properties are as follows:
1. Appearance: white crystal or powder;
2. Solubility: soluble in anhydrous alcohol, ether and organic solvent, slightly soluble in water;
3. Melting Point: about 140-142 ℃;
4. Stability: It is relatively stable at regular temperatures, but may decompose under strong acid or alkali conditions.
2,2-difluoro-2-(4-(trifluoromethoxy)phenyl)acetic acid has some applications in some fields, for example:
1. Pesticide: can be used to prepare pesticide intermediates or pesticides;
2. Drug synthesis: It can be used as one of the intermediates of drug synthesis and participate in the development and preparation of new drugs.
Its preparation method can be achieved through the following steps:
1. Reacting trifluorotoluene with hydrofluoric acid to generate 4-(trifluoromethyl) phenyl fluoride;
2. Reacting the compound obtained in step 1 with 2,2-difluoroethanol to generate 2,2-difluoro -2-(4-(trifluoromethoxy) phenyl) ethanol;
3. Finally, 2,2-difluoro-2-(4-(trifluoromethoxy)phenyl) ethanol was subjected to acid-catalyzed esterification to obtain 2,2-difluoro-2-(4-(trifluoromethoxy)phenyl)acetic acid.
Safety information of the compound If it comes into contact with the skin, it may cause irritation and allergic reactions, so during operation, you should wear appropriate protective equipment and ensure good ventilation. In addition, it may also cause potential harm to the environment, so it needs to be handled and disposed of in accordance with relevant regulations when used.
Last Update：2024-04-09 21:00:56