2,2-difluoro-2-(4-(trifluoromethyl)phenyl)ethan-1-ol - Names and Identifiers
2,2-difluoro-2-(4-(trifluoromethyl)phenyl)ethan-1-ol - Physico-chemical Properties
| Molecular Formula | C9H7F5O
|
| Molar Mass | 226.143296 |
2,2-difluoro-2-(4-(trifluoromethyl)phenyl)ethan-1-ol - Introduction
2,2-difluoro-2-(4-(trifluoromethyl)phenyl)ethanol is an organic compound with the chemical formula C10H8F5O.
The compound is in the form of a colorless liquid or solid. It is almost insoluble in water at room temperature and has a lower boiling point and melting point. It is an aromatic compound with strong fluorinated properties and trifluoromethyl groups.
2,2-difluoro-2-(4-(trifluoromethyl)phenyl)ethanol is widely used in organic synthesis. It can be used as a fluorination reagent in organic synthesis reactions for introducing fluorine atoms into molecules. It can also be used as an intermediate in the synthesis of drugs and pesticides.
The compound can be synthesized by a variety of methods. A common method of preparation is by condensation of p-nitrobenzene, tert-butylmagnesium fluoride and formaldehyde in the presence of a catalyst. Alternatively, it can be obtained by reacting 4-trifluoromethylphenylacetaldehyde with difluoromethylamine under basic conditions.
Safety precautions are required when using 2,2-difluoro-2-(4-(trifluoromethyl)phenyl)ethanol. The compound is irritating and may cause damage to the eyes, skin and respiratory system, so protective gloves, face masks and goggles are required for handling. In addition, they should avoid contact with fire sources to avoid fire or explosion. In storage and handling, appropriate safety measures need to be taken to prevent accidents.
Last Update：2024-04-09 20:52:54