2,2-二氯丙酸
2,2-Dichloropropionic acid
CAS: 75-99-0
Molecular Formula: C3H4Cl2O2
2,2-二氯丙酸 - Names and Identifiers
| Name | 2,2-Dichloropropionic acid |
| Synonyms | s1315 Dalapon Proprop dowponm Kenapon Liropon 2,2-dichloropropanoate 2,2-Dichloropropionic acid kyselina2,2-dichlorpropionova Propionic acid, 2,2-dichloro- Kyselina 2,2-dichlorpropionova |
| CAS | 75-99-0 |
| EINECS | 200-923-0 |
| InChI | InChI=1/C3H4Cl2O2/c1-3(4,5)2(6)7/h1H3,(H,6,7)/p-1 |
2,2-二氯丙酸 - Physico-chemical Properties
| Molecular Formula | C3H4Cl2O2 |
| Molar Mass | 142.97 |
| Density | 1.4014 |
| Melting Point | 166°C (dec.) |
| Boling Point | 202°C |
| Flash Point | >110°C |
| Water Solubility | 50.2 g/100 mL |
| Vapor Presure | 0.282mmHg at 25°C |
| Appearance | Liquid |
| Color | Colorless to Light yellow |
| Merck | 14,2802 |
| BRN | 1750149 |
| pKa | pK1:2.06 (25°C) |
| Storage Condition | 0-6°C |
| Sensitive | Moisture Sensitive |
| Refractive Index | 1.4544 |
| Physical and Chemical Properties | Colorless or light yellow liquid. Boiling point 185-190 ℃,98-99 ℃(2.67kPa),90-92 ℃(1.87kPa), relative density 1.4014(20/4 ℃), refractive index 1.4551. Soluble in water, alcohol, alkali solution and ether. It can volatilize with water vapor and is corrosive to iron. Its sodium salt is Crystal. 174-176 degrees C decomposition, 25 degrees in water solubility of 45g/100ml, about 70 degrees C decomposition. |
| Use | For organic synthesis and biochemical research |
2,2-二氯丙酸 - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R38 - Irritating to the skin R41 - Risk of serious damage to eyes R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R40 - Limited evidence of a carcinogenic effect R36/37/38 - Irritating to eyes, respiratory system and skin. R11 - Highly Flammable |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S36 - Wear suitable protective clothing. S16 - Keep away from sources of ignition. S24 - Avoid contact with skin. S9 - Keep container in a well-ventilated place. |
| UN IDs | 3265 |
| WGK Germany | 3 |
| RTECS | UF0690000 |
| HS Code | 29159000 |
| Hazard Class | 8 |
| Packing Group | III |
| Toxicity | LD50 in male, female rats (mg/kg): 7126, 6936 orally (Gaines, Linder) |
2,2-二氯丙酸 - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Overview | 2, 2-dichloropropionic acid is useful as a pharmaceutical synthesis intermediate. If inhaling 2, 2-dichloropropionic acid, move the patient to fresh air; If there is skin contact, remove contaminated clothing and rinse the skin thoroughly with soap and water, if the eyes are in contact, the eyelids should be separated, washed with running water or normal saline, and immediately seek medical treatment; If you eat, immediately rinse your mouth, prohibit emesis, should immediately seek medical treatment. |
| preparation | 2, 2-dichloropropionic acid was prepared as follows: 1.7 (2.3g, 1 Mass%)60% nitric acid to 100 ml density d4201.393 and purity of not less than 98.5% of 2, 2-dichloropropionic acid, then the product is maintained in isothermal conditions until gas release is completely stopped, A solution of 10g of SeO2 in 10 ml of water was then added as a solution of 2 SeO3. The resulting solution was stirred at a temperature of 50-60 °c for 12 hours to obtain 151.5G of a transparent yellow semifinished solution. Quality parameters: d4201.386,2, 2-dichloropropionic acid content-91.7%, water-7.8%, selenium-0.68%, nitrate ion-0.04%. |
| purpose | is used as intermediate of medicine and pesticide. From 2, 2-dichloropropionic acid and 2,4, 5-trichlorophenoxyethanol can be prepared atractylodes. The product as a herbicide, that is, the grass, also known as darapone. Thallus is often refers to 2, 2-dichloropropionic acid sodium, is a kind of inhibition of annual and perennial grass weeds in the absorption of herbicide, through the leaf after the role of the whole grass, in addition, a small part of the root system was also absorbed by the root system. One week after the application, the grass leaves began to turn yellow and died completely about one month later. for organic synthesis and biochemical studies |
| production method | 1. Derived from the chlorination of propionic acid. 2. Catalytic hydrogenation of acrylonitrile to produce propionitrile, followed by chlorination and hydrolysis. |
| category | pesticide |
| toxicity grade | poisoning |
| Acute toxicity | oral-rat LD50: 970 mg/kg |
| stimulation data | Skin-rabbit 0.1 mg/24 h |
| flammability hazard characteristics | toxic chloride gases from combustion |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; It is stored and transported separately from food raw materials |
| extinguishing agent | dry powder, foam, sand |
| Occupational Standard | TLV-TWA 6 mg/m3 |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 02:00:11
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Mobile: 86+15671228036
QQ: 2853786052
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Multiple Specifications
Product Name: 2,2-Dichloropropionic Acid Visit Supplier Webpage Request for quotationCAS: 75-99-0
Tel: 18301782025
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Mobile: 18021002903
QQ: 3008007409
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