2,3,5-trifluroophenylacetic acid

2,3,5-trifluroophenylacetic acid - Names and Identifiers

Name	2,3,5-Trifluorophenylacetic acid
Synonyms	RARECHEM AL BO 0711 Sitagliptin Impurity 79 2,3,5-trifluroophenylacetic acid 2,3,5-TRIFLUOROPHENYLACETIC ACID 2,3,5-Trifluorophenylacetic acid 2,3,5-(trifluorophenyl)acetic acid 2-(2,3,5-Trifluorophenyl)acetic acid Benzeneacetic acid, 2,3,5-trifluoro-
CAS	132992-28-0
InChI	InChI=1/C8H5F3O2/c9-5-1-4(2-7(12)13)8(11)6(10)3-5/h1,3H,2H2,(H,12,13)

2,3,5-trifluroophenylacetic acid - Physico-chemical Properties

Molecular Formula	C8H5F3O2
Molar Mass	190.12
Density	1.468±0.06 g/cm3(Predicted)
Boling Point	246.3±35.0 °C(Predicted)
Flash Point	102.8°C
Vapor Presure	0.0146mmHg at 25°C
pKa	3.61±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.488
MDL	MFCD00083547

2,3,5-trifluroophenylacetic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
Hazard Class	IRRITANT

2,3,5-trifluroophenylacetic acid - Introduction

2,3,5-Trifluorophenylacetic acid (2,3,5-Trifluorophenylacetic acid) is an organic compound with the chemical formula C8H5F3O2. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: 2,3, 5-Trifluorophenylacetic acid is a white crystalline solid.
-Melting point: about 75-78 degrees Celsius.
-Boiling point: about 220-265 degrees Celsius.
-Solubility: Its solubility in water is low, but it can be dissolved in organic solvents such as methanol, ethanol and dichloromethane.

Use:
-Chemical synthesis: 2,3, 5-trifluorophenylacetic acid can be used as a reagent and intermediate in organic synthesis for the synthesis of other compounds.
-Pesticides: It can also be used to synthesize certain pesticides and insecticides.

Preparation Method:
- 2,3, 5-Trifluorophenylacetic acid can be prepared by fluorination of phenylacetonitrile. The specific steps are first reacting phenylacetonitrile with copper trifluoride, and then performing a hydrolysis reaction to obtain the target product.

Safety Information:
- 2,3, 5-Trifluorophenylacetic acid is generally considered to be a relatively safe compound.
-When handling it, observe normal laboratory safety practices, such as wearing appropriate protective gloves, goggles and laboratory coats.
-In case of inhalation, contact with skin or ingestion, proper first aid and cleaning should be carried out in a timely manner.
-During handling and storage, avoid contact with oxidants and strong bases to avoid dangerous reactions.
-When handling waste, correct treatment and disposal should be carried out in accordance with local regulations.

Please note that the above information is for reference only. Please follow the actual situation and applicable regulations when using 2,3, 5-trifluorophenylacetic acid, and consult professional chemists when needed.

Last Update：2024-04-10 22:29:15