2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno(9,10)cyclodeca(1,2-b)furan-9(1aH)-one
Parthenolide
CAS: 20554-84-1;29552-41-8
Molecular Formula: C15H20O3
2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno(9,10)cyclodeca(1,2-b)furan-9(1aH)-one - Names and Identifiers
2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno(9,10)cyclodeca(1,2-b)furan-9(1aH)-one - Physico-chemical Properties
| Molecular Formula | C15H20O3 |
| Molar Mass | 248.32 |
| Density | 1.13g/cm3 |
| Melting Point | 115-116ºC(lit.) |
| Boling Point | 394.095°C at 760 mmHg |
| Specific Rotation(α) | -81.4 (c, 1.04 in CHCl3) |
| Flash Point | 166.344°C |
| Solubility | Soluble in organic solvents such as acetone, ethyl acetate, DMSO, etc., insoluble in water. |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Brown yellow powder |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.533 |
| MDL | MFCD00134592 |
| Physical and Chemical Properties | Soluble in organic solvents such as acetone, ethyl acetate, DMSO, etc., insoluble in water. Tsoongiodendronodorum Chun, a plant of the genus Magnolia, comes from the genus Magnolia. |
2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno(9,10)cyclodeca(1,2-b)furan-9(1aH)-one - Reference
| Reference Show more | 1. Su Jiezhi, Zheng Liping, Zhong Junhua, Fan Pingming, Chen Zhilin. Parthenolide induces autophagy in breast cancer MCF-7 cells through ERK/MAPK pathway [J]. Chinese Pharmacist, 2019,22(07):1236-1239. |
2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno(9,10)cyclodeca(1,2-b)furan-9(1aH)-one - Introduction
Parthenolide is a common organic compound with the chemical formula C15H12O5. The following is an introduction to the nature, use, formulation, and safety information of Parthenolide.
Nature:
Parthenolide is a white crystalline solid with a sweet taste. It has a melting point of about 228-230°C and is soluble in some organic solvents, such as ethanol, acetone and ethyl acetate.
Use:
Parthenolide is widely used in the food, beverage and pharmaceutical industries. It has a good sweetness. Compared with sucrose, its sweetness is about 300 times that of sucrose, but the calories are very low. Therefore, Parthenolide is commonly used as a low-calorie sweetener for the manufacture of low-sugar, low-calorie foods and beverages.
Preparation Method:
Parthenolide can be obtained by chemical synthesis. A common method is to chemically convert white chrysanthemum sugar (a naturally occurring substance) into Parthenolide through steps such as acid catalysis.
Safety Information:
Parthenolide is widely regarded as a safe food additive with very low toxicity to humans. In food processing, very small amounts are usually required to achieve the desired sweetening effect. However, for some people, there may be an allergy to Parthenolide or an adverse reaction. Therefore, when using Parthenolide, the appropriate dosage limits should be observed, as well as the use according to the individual constitution and the doctor's advice.
In General, Parthenolide is a safe, low-calorie, high-sweetness food additive that is widely used in the manufacture of low-sugar, low-calorie foods and beverages.
Nature:
Parthenolide is a white crystalline solid with a sweet taste. It has a melting point of about 228-230°C and is soluble in some organic solvents, such as ethanol, acetone and ethyl acetate.
Use:
Parthenolide is widely used in the food, beverage and pharmaceutical industries. It has a good sweetness. Compared with sucrose, its sweetness is about 300 times that of sucrose, but the calories are very low. Therefore, Parthenolide is commonly used as a low-calorie sweetener for the manufacture of low-sugar, low-calorie foods and beverages.
Preparation Method:
Parthenolide can be obtained by chemical synthesis. A common method is to chemically convert white chrysanthemum sugar (a naturally occurring substance) into Parthenolide through steps such as acid catalysis.
Safety Information:
Parthenolide is widely regarded as a safe food additive with very low toxicity to humans. In food processing, very small amounts are usually required to achieve the desired sweetening effect. However, for some people, there may be an allergy to Parthenolide or an adverse reaction. Therefore, when using Parthenolide, the appropriate dosage limits should be observed, as well as the use according to the individual constitution and the doctor's advice.
In General, Parthenolide is a safe, low-calorie, high-sweetness food additive that is widely used in the manufacture of low-sugar, low-calorie foods and beverages.
Last Update：2024-04-09 20:45:29
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