2,3-DIFLUOROPYRIDINE
2,3-Difluoropyridine
CAS: 1513-66-2
Molecular Formula: C5H3F2N
2,3-DIFLUOROPYRIDINE - Names and Identifiers
| Name | 2,3-Difluoropyridine |
| Synonyms | 2,3-Difluorpyridin 2,3-difluorpyridine 2,3-Difluoropyridine 2,3-DIFLUOROPYRIDINE Pyridine, 2,3-difluoro- 2,3-DIFLUOROPYRIDINE(RS20007306) |
| CAS | 1513-66-2 |
| InChI | InChI=1/C5H3F2N/c6-4-2-1-3-8-5(4)7/h1-3H |
2,3-DIFLUOROPYRIDINE - Physico-chemical Properties
| Molecular Formula | C5H3F2N |
| Molar Mass | 115.08 |
| Density | 1.265 g/mL at 25 °C |
| Boling Point | 125-126°C |
| Flash Point | 125-126°C |
| Vapor Presure | 21.6mmHg at 25°C |
| Appearance | clear liquid |
| Color | Colorless to Light yellow |
| pKa | -2.85±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | n20/D 1.427 |
| Physical and Chemical Properties | Light yellow liquid |
2,3-DIFLUOROPYRIDINE - Risk and Safety
| Risk Codes | R10 - Flammable R36/37/38 - Irritating to eyes, respiratory system and skin. R50 - Very Toxic to aquatic organisms R41 - Risk of serious damage to eyes R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S25 - Avoid contact with eyes. S16 - Keep away from sources of ignition. |
| UN IDs | 1993 |
| WGK Germany | 2 |
| HS Code | 29333990 |
| Hazard Note | Toxic |
| Hazard Class | 3 |
| Packing Group | III |
2,3-DIFLUOROPYRIDINE - Introduction
2,3-difluoropyridine, chemical formula C5H3F2N, is an organic compound. The following is a description of the nature, use, preparation and safety information of 2,3-difluoropyridine:
Nature:
1. Appearance: 2,3-difluoropyridine is a colorless liquid with a special aromatic smell.
2. Density: The density of 2,3-difluoropyridine is 1.292g/cm3.
3. Solubility: 2,3-difluoropyridine is soluble in polar organic solvents, such as ethanol, carbon tetrachloride and acetone, but almost insoluble in water.
Use:
1. As a solvent: 2,3-difluoropyridine is often used as a solvent in organic synthesis, especially suitable for fluorination reactions and acidic reactions.
2. Pharmaceutical Chemistry: 2,3-difluoropyridine can be used to synthesize drugs or drug intermediates.
Method:
There are many preparation methods for 2,3-difluoropyridine, one of which is commonly used is obtained by reacting p-fluorobenzene and pyridine in the presence of hydrofluoric acid. Specific reaction conditions and Operation steps can be adjusted according to actual needs.
Safety Information:
1. Storage: 2,3-difluoropyridine should be stored in a cool, dry place, away from fire sources and incompatible substances.
2. Precautions for use: Wear protective gloves, safety glasses and goggles when using. Avoid inhalation, ingestion or contact with skin. Good ventilation should be maintained during operation.
3. Toxicity: 2,3-difluoropyridine is an organic compound with certain toxicity. Exposure to high concentrations of 2,3-difluoropyridine may cause irritation and damage to the human body. In the event of an accident, medical assistance should be sought immediately.
Please note that when using 2,3-difluoropyridine or other chemicals, you should follow the relevant safety procedures, and properly manage and dispose of chemical waste, to ensure personal safety and environmental protection.
Nature:
1. Appearance: 2,3-difluoropyridine is a colorless liquid with a special aromatic smell.
2. Density: The density of 2,3-difluoropyridine is 1.292g/cm3.
3. Solubility: 2,3-difluoropyridine is soluble in polar organic solvents, such as ethanol, carbon tetrachloride and acetone, but almost insoluble in water.
Use:
1. As a solvent: 2,3-difluoropyridine is often used as a solvent in organic synthesis, especially suitable for fluorination reactions and acidic reactions.
2. Pharmaceutical Chemistry: 2,3-difluoropyridine can be used to synthesize drugs or drug intermediates.
Method:
There are many preparation methods for 2,3-difluoropyridine, one of which is commonly used is obtained by reacting p-fluorobenzene and pyridine in the presence of hydrofluoric acid. Specific reaction conditions and Operation steps can be adjusted according to actual needs.
Safety Information:
1. Storage: 2,3-difluoropyridine should be stored in a cool, dry place, away from fire sources and incompatible substances.
2. Precautions for use: Wear protective gloves, safety glasses and goggles when using. Avoid inhalation, ingestion or contact with skin. Good ventilation should be maintained during operation.
3. Toxicity: 2,3-difluoropyridine is an organic compound with certain toxicity. Exposure to high concentrations of 2,3-difluoropyridine may cause irritation and damage to the human body. In the event of an accident, medical assistance should be sought immediately.
Please note that when using 2,3-difluoropyridine or other chemicals, you should follow the relevant safety procedures, and properly manage and dispose of chemical waste, to ensure personal safety and environmental protection.
Last Update：2024-04-09 15:17:52
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CAS: 1513-66-2
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