2,3-DIMETHYLPHENYLBORONIC ACID

2,3-DIMETHYLPHENYLBORONIC ACID - Names and Identifiers

Name	2,3-Dimethylbenzeneboronic acid
Synonyms	AKOS BRN-0096 2,3-dimethyl acid RARECHEM AH PB 0184 O-XYLENE-3-BORONIC ACID 2,3-Dimethylphenylboronic 2,3-DIMETHYLPHENYLBORONIC ACID 2,3-Dimethylphenylboronic acid 2,3-DIMETHYLBENZENEBORONIC ACID 2,3-Dimethylbenzeneboronic acid 2,3-Dimethylphenylboronic Acid (contains varying amounts of Anhydride)
CAS	183158-34-1
EINECS	679-696-9
InChI	InChI=1/C8H11BO2/c1-6-4-3-5-8(7(6)2)9(10)11/h3-5,10-11H,1-2H3

2,3-DIMETHYLPHENYLBORONIC ACID - Physico-chemical Properties

Molecular Formula	C8H11BO2
Molar Mass	149.98
Density	1.07±0.1 g/cm3(Predicted)
Melting Point	174-180°C(lit.)
Boling Point	312.6±52.0 °C(Predicted)
Flash Point	142.8°C
Solubility	soluble in Methanol
Vapor Presure	0.000224mmHg at 25°C
Appearance	grayish white powder
Color	White
BRN	8050763
pKa	8.70±0.58(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.523
MDL	MFCD01863524

2,3-DIMETHYLPHENYLBORONIC ACID - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29163990
Hazard Class	IRRITANT

2,3-DIMETHYLPHENYLBORONIC ACID - Introduction

2,3-dimethylbenzeneboronic acid, also known as 2,3-dimethylphenylboronic acid, is an organic compound. The following is an introduction to its nature, use, formulation and safety information:

Nature:
-Appearance: 2,3-dimethylbenzeneboronic acid is white to light yellow crystal or crystalline powder.
-Solubility: It is soluble in many organic solvents, such as ethanol, acetone and dichloromethane. Only slightly soluble in water.

Use:
-2,3-dimethylbenzeneboronic acid is commonly used in metal-catalyzed reactions in organic synthesis. It is an important Organoboron reagent, commonly used in metal-catalyzed boronation reactions, coupling reactions and reduction reactions.
-It can also be used as a precursor of biomarkers and ligands for drug synthesis and chemical biology research.

Method:
-The preparation method of 2,3-dimethylbenzeneboronic acid includes the following steps:
1.2,3-dimethylbenzaldehyde and triphenylboron are reacted with alkali catalyst at low temperature with organic solvent as carrier.
2. After the reaction, the product can be obtained by crystallization.

Safety Information:
- 2,3-dimethylbenzeneboronic acid is relatively safe under normal use conditions. However, General Chemical Laboratory practices and safe practices should be observed.
-When in contact with skin, eyes or when taking, rinse immediately with plenty of water. If you feel seriously ill, you should seek medical help.
-It should be stored in a dry, cool place, away from fire sources and strong oxidants.

Last Update：2024-04-09 20:45:29