2,4,5,6(1H,3H)-Pyrimidinetetrone, 2,4,5,6-Tetraoxypyrimidine, 5,6-Dioxyuracil
Alloxan monohydrate
CAS: 2244-11-3
Molecular Formula: C4H4N2O5
2,4,5,6(1H,3H)-Pyrimidinetetrone, 2,4,5,6-Tetraoxypyrimidine, 5,6-Dioxyuracil - Names and Identifiers
| Name | Alloxan monohydrate |
| Synonyms | MESOXALYLUREA 5,6-DIOXYURACIL Alloxan monohydrate LABOTEST-BB LT00138148 MESOXALYLUREA, MONOHYDRATE 5,6-DIOXYURACIL MONOHYDRATE mesoxalylcarbamidemonohydrate Mesoxalylcarbamide monohydrate 2,4,5,6(1H,3H)-Pyrimidinetetrone hydrate 2,4,5,6-tetraoxohexahydropyrimidinehydrate 2,4,5,6(1H,3H)-Pyrimidinetetrone, 2,4,5,6-Tetraoxypyrimidine, 5,6-Dioxyuracil |
| CAS | 2244-11-3 |
| EINECS | 607-078-0 |
| InChI | InChI=1/C4H2N2O4.H2O/c7-1-2(8)5-4(10)6-3(1)9;/h(H2,5,6,8,9,10);1H2 |
2,4,5,6(1H,3H)-Pyrimidinetetrone, 2,4,5,6-Tetraoxypyrimidine, 5,6-Dioxyuracil - Physico-chemical Properties
| Molecular Formula | C4H4N2O5 |
| Molar Mass | 160.09 |
| Melting Point | 255°C (dec.)(lit.) |
| Boling Point | 374.1°C at 760 mmHg |
| Flash Point | 180°C |
| Water Solubility | Soluble in water, ethanol, acetone, glacial acetic acid and methanol. Slightly soluble in chloroform, petroleum ether, toluene, ethyl acetate and acetic anhydride. Insoluble in ether. |
| Solubility | Soluble in water (50 g/L), ethanol, acetone, glacial acetic acid, methanol, and Slightly |
| Vapor Presure | 8.59E-07mmHg at 25°C |
| Appearance | White to white-like crystalline powder |
| Color | Off-white to beige-yellow |
| Merck | 14,282 |
| BRN | 5309394 |
| Storage Condition | 2-8°C |
| Sensitive | Air Sensitive |
| MDL | MFCD00149399 |
2,4,5,6(1H,3H)-Pyrimidinetetrone, 2,4,5,6-Tetraoxypyrimidine, 5,6-Dioxyuracil - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
| RTECS | UW0492000 |
| TSCA | Yes |
| HS Code | 29335995 |
2,4,5,6(1H,3H)-Pyrimidinetetrone, 2,4,5,6-Tetraoxypyrimidine, 5,6-Dioxyuracil - Reference
| Reference Show more | 1. Pang Zengxiong, Huang Yufeng, Chen Ziling, et al. Animal Experimental Evaluation of Auxiliary Hypoglycemic Function of Pueraria lobata Bitter Gourd Health Food [J]. Modern Food, 2017, 15(v.27;No.120):88-91. 2. Yin Hongli, Zhao Xin, Tong Lili, et al. Hypoglycemic Function of Auricularia auricula Polysaccharide in Vitro and in Vivo [J]. Food Science, 2015, 36(021):221-226. 3. [IF = 1.718] HUA Li Yue et al."Determination of SOD in black ginger extract and its effect on the liver of rats with type 2 diabetes." Food Sci Tech-Brazil. 2022 Mar;42: |
2,4,5,6(1H,3H)-Pyrimidinetetrone, 2,4,5,6-Tetraoxypyrimidine, 5,6-Dioxyuracil - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Physiological effects | Alloxan has a special destructive effect on the islet of Langerhans, the islet of the pancreas (islet of pancreas islet). The secretion of insulin causes experimental alloxan diabetes (alloxan diabetes) in animals. The same effect can be caused by one injection of streptozotocin (streptozo), a nitro derivative of glucosamine. |
| Preparation | The original alloxan is made from nitric acid oxidation of uric acid, and it can also be made from chromium trioxide oxidation of barbituric acid. |
| Use | Aurea is an acylurea of acetone diacid, which can be synthesized by the oxidation of uric acid. It has a special destructive effect on the beta cells of islet of Langerhans (islet of pancreas islet) in the pancreas, suspending the secretion of insulin, and causing experimental alloxan diabetes in animals (alloxan diabetes). The same effect can be caused by one injection of streptozotocin (streptozo), a nitro derivative of glucosamine. |
Last Update：2024-04-09 20:49:11
Supplier List
Multiple SpecificationsSpot supply
Product Name: Alloxan monohydrate Visit Supplier Webpage Request for quotationCAS: 2244-11-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Multiple SpecificationsSpot supply
Product Name: Alloxan monohydrate Visit Supplier Webpage Request for quotationCAS: 2244-11-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History