2,5,8,11,14,17,20,23-Octaoxahexacosan-26-oic acid,MeO-(dPEG8)-COOH

Name	4,7,10,13,16,19,22,25-Octaoxahexacosanoic acid
Synonyms	mPEG8-COOH m-PEG8-acid m-dPEG8-acid MPEG7-CH2CH2COOH MPEG7-OCH2CH2COOH mPEG7-propionic acid 4,7,10,13,16,19,22,25-Octaoxahexacosanoic acid 2,5,8,11,14,17,20,23-Octaoxahexacosan-26-oic acid,MeO-(dPEG8)-COOH
CAS	1093647-41-6

Molecular Formula	C18H36O10
Molar Mass	412.47
Density	1.111±0.06 g/cm3(Predicted)
Boling Point	503.0±50.0 °C(Predicted)
pKa	4.28±0.10(Predicted)
Storage Condition	-20°C
In vitro study	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

use	4,7,10,13,16,19,22,25-octaoxane acid is used to detect antibiotic residues by nano-gold probe surface plasmon resonance method.
biological activity	m-PEG7-CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-coupled drugs (ADC). m-PEG7-CH2COOH is also a PEG-based PROTAC linker, which can be used for PROTAC synthesis.
target	Non-cleavable PEGs
in vitro study	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Last Update：2024-04-09 21:04:16

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