2,5-Bis(trifluoromethyl)benzoyl chloride

2,5-Bis(trifluoromethyl)benzoyl chloride - Names and Identifiers

Name	2,5-bis(trifluoromethyl)benzoyl chloride
Synonyms	SKL1172 2,5-bis(trifluoromethyl)benzoyl chloride 2,5-Bis(trifluoromethyl)benzoyl chloride 2,5-BIS(TRIFLUOROMETHYL)BENZOYL CHLORIDE Benzoyl chloride, 2,5-bis(trifluoromethyl)-
CAS	393-82-8
InChI	InChI=1/C8H6FNO4/c1-14-8(11)6-4-5(9)2-3-7(6)10(12)13/h2-4H,1H3

2,5-Bis(trifluoromethyl)benzoyl chloride - Physico-chemical Properties

Molecular Formula	C9H3ClF6O
Molar Mass	276.56
Density	1.528g/mLat 25°C(lit.)
Boling Point	185
Flash Point	165°F
Vapor Presure	0.00346mmHg at 25°C
Storage Condition	2-8℃
Sensitive	Lachrymatory
Refractive Index	n20/D 1.4315(lit.)

2,5-Bis(trifluoromethyl)benzoyl chloride - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 3265 8/PG 2
WGK Germany	3
Hazard Note	Corrosive/Lachrymatory
Hazard Class	8
Packing Group	III

2,5-Bis(trifluoromethyl)benzoyl chloride - Introduction

2,5-bis(trifluoromethyl)benzoyl chloride is an organic compound with the chemical formula C9H2ClF6O. It is a colorless liquid with a pungent odor. The following is a detailed description of the nature, use, preparation and safety information of 2,5-bis(trifluoromethyl)benzoyl chloride:

Nature:
-Appearance: colorless liquid
-Molecular weight: 250.56g/mol
-Boiling Point: 161-163°C
-Melting point:-5°C
-Density: 1.51g/cm³
-Refractive Index: 1.4450(20°C)

Use:
2,5-bis(trifluoromethyl)benzoyl chloride is an important reagent and is widely used in many organic synthesis reactions. It can be used to synthesize compounds with a variety of functions, such as ketones, ethers, esters, azides, etc. It can also be used as an intermediate in the synthesis of drugs.

Preparation Method:
In general, the preparation of 2,5-bis(trifluoromethyl)benzoyl chloride can be obtained by reacting 2,5-bis-trifluoromethylbenzoic acid with an excess of thionyl chloride (SO2Cl2). The reaction needs to be carried out at an appropriate temperature, and drying and gas purification treatment are required.

Safety Information:
2,5-bis(trifluoromethyl)benzoyl chloride is an irritating compound that may be irritating to the eyes, skin, and respiratory tract. Care should be taken to avoid contact during use and to ensure that it is operated in a well-ventilated place. Avoid inhaling its vapors and avoid swallowing it or touching internal organs. Wear appropriate protective gloves, goggles and protective clothing during use. In case of accidental contact, rinse immediately with plenty of water and seek medical assistance. In use and storage, should follow the relevant safety procedures.

Last Update：2024-04-09 02:00:45