2-(3,4-dihydroxyphenyl)acetamide
2-(3,4-dihydroxyphenyl)acetamide
CAS: 1129-53-9
Molecular Formula: C8H9NO3
2-(3,4-dihydroxyphenyl)acetamide - Names and Identifiers
| Name | 2-(3,4-dihydroxyphenyl)acetamide |
| Synonyms | Dopamine Impurity 22 Dopamine Impurity 27 3,4-DIHYDROXYPHENYLACETAMIDE 3,4-dihydroxyenzeneacetamide 3,4-Dihydroxybenzeneacetamide Benzeneacetamide, 3,4-dihydroxy- 2-(3,4-Dihydroxyphenyl)acetamide 2-(3,4-dihydroxyphenyl)acetamide 2-(3,4-dihydroxyphenyl)ethanamide |
| CAS | 1129-53-9 |
| EINECS | 214-451-8 |
| InChI | InChI=1/C8H9NO3/c9-8(12)4-5-1-2-6(10)7(11)3-5/h1-3,10-11H,4H2,(H2,9,12) |
2-(3,4-dihydroxyphenyl)acetamide - Physico-chemical Properties
| Molecular Formula | C8H9NO3 |
| Molar Mass | 167.16 |
| Density | 1.394g/cm3 |
| Boling Point | 478°C at 760 mmHg |
| Flash Point | 242.9°C |
| Vapor Presure | 9.25E-10mmHg at 25°C |
| Refractive Index | 1.638 |
2-(3,4-dihydroxyphenyl)acetamide - Introduction
3,4-Dihydroxyphenylacetamide, also known as 3,4-Dihydroxyacetanilide, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3,4-Dihydroxyphenylacetamide is a white crystalline solid.
-Solubility: It has limited solubility in water and is more soluble in organic solvents.
-Melting point: The melting point of 3,4-dihydroxyphenylacetamide is about 177°C.
Use:
-Pharmaceutical Field: 3,4-Dihydroxyphenylacetamide is commonly used as an intermediate for certain drugs, such as the synthesis of acetaminophen (a common antipyretic).
-Cosmetics: Due to its antioxidant properties, 3,4-dihydroxyphenylacetamide can be used in skin care products and anti-aging products.
Preparation Method:
The method for preparing 3,4-dihydroxyphenylacetamide can be obtained by a reduction reaction of acetophenone. The specific steps include reacting acetophenone with acetic anhydride through a methanol solution to produce 3,4-dihydroxyphenylacetamide.
Safety Information:
- 3,4-Dihydroxyphenylacetamide is not known to have definite toxicity. However, as a chemical substance, appropriate laboratory safety measures should be taken when handling, such as wearing protective gloves, goggles and laboratory coats.
-Avoid contact with skin, eyes and inhalation of dust. In case of discomfort or accidental exposure, medical help should be sought immediately.
-During use or storage, keep away from combustibles and oxidants and follow relevant safety procedures.
Nature:
-Appearance: 3,4-Dihydroxyphenylacetamide is a white crystalline solid.
-Solubility: It has limited solubility in water and is more soluble in organic solvents.
-Melting point: The melting point of 3,4-dihydroxyphenylacetamide is about 177°C.
Use:
-Pharmaceutical Field: 3,4-Dihydroxyphenylacetamide is commonly used as an intermediate for certain drugs, such as the synthesis of acetaminophen (a common antipyretic).
-Cosmetics: Due to its antioxidant properties, 3,4-dihydroxyphenylacetamide can be used in skin care products and anti-aging products.
Preparation Method:
The method for preparing 3,4-dihydroxyphenylacetamide can be obtained by a reduction reaction of acetophenone. The specific steps include reacting acetophenone with acetic anhydride through a methanol solution to produce 3,4-dihydroxyphenylacetamide.
Safety Information:
- 3,4-Dihydroxyphenylacetamide is not known to have definite toxicity. However, as a chemical substance, appropriate laboratory safety measures should be taken when handling, such as wearing protective gloves, goggles and laboratory coats.
-Avoid contact with skin, eyes and inhalation of dust. In case of discomfort or accidental exposure, medical help should be sought immediately.
-During use or storage, keep away from combustibles and oxidants and follow relevant safety procedures.
Last Update：2024-04-09 15:17:51
