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2-甲氧基-4-氟苯胺

4-Fluoro-2-methoxyaniline

CAS: 450-91-9

Molecular Formula: C7H8FNO

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2-甲氧基-4-氟苯胺 - Names and Identifiers

Name 4-Fluoro-2-methoxyaniline
Synonyms o-Anisidine, 4-fluoro-
2-Amino-5-fluoroanisole
2-Methoxy-4-fluoroaniline
4-FLUORO-2-METHOXYANILINE
4-Fluoro-2-methoxyaniline
4-Fluoro-2-MethoxybenzenaMine
4-Fluoro-2-methoxy-phenylamine
benzenamine, 4-fluoro-2-methoxy-
4-Fluoro-o-anisidine, 2-Amino-5-fluoroanisole
2-AMino-5-fluoroanisole[4-Fluoro-2-Methoxyaniline]
CAS 450-91-9
EINECS 814-457-6
InChI InChI=1/C7H8FNO/c1-10-7-4-5(8)2-3-6(7)9/h2-4H,9H2,1H3

2-甲氧基-4-氟苯胺 - Physico-chemical Properties

Molecular FormulaC7H8FNO
Molar Mass141.14
Density1.176±0.06 g/cm3 (20 ºC 760 Torr)
Boling Point215℃ (756 Torr)
Flash Point79.5±21.8℃
Vapor Presure0.22mmHg at 25°C
AppearanceSolid
ColorColorless to Brown
pKa4.60±0.10(Predicted)
Storage ConditionKeep in dark place,Inert atmosphere,Room temperature
Refractive Index1.5400 to 1.5440
MDLMFCD00077536

2-甲氧基-4-氟苯胺 - Risk and Safety

UN IDs2810
Hazard Class6.1
Packing GroupⅢ

2-甲氧基-4-氟苯胺 - Reference Information

Uses 4-fluoro-2-o-methoxyaniline is a useful synthetic intermediate, which can be used to prepare ortho-substituted phenylurea as 5-Hydroxytryptamine (5-HT3) receptor antagonist, is also used to synthesize hydroxamic acid and its prodrugs as inhibitors of the light chain of botulinum neurotoxin A.
Synthesis method
Using 4-fluoro-2-o-methoxynitrobenzene as the starting material, the target compound 4-fluoro-2-o-methoxyaniline is prepared by hydrogenation reduction reaction. The synthesis reaction formula is as follows:
Last Update:2024-04-09 02:00:08
2-甲氧基-4-氟苯胺
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View History
2-甲氧基-4-氟苯胺
MAGNESIUM HYDROGEN PHOSPHATE-3-HYDRATE
2-氟-4-碘尼古丁酸
2-[[(3AR,4S,6R,6AS)-6-氨基-2,2-二甲基四氢-3AH-环戊二烯并[D][1,3]-二氧杂环戊-4-基]氧基]-1-乙醇 L-酒石酸盐
2-氯-3-吡啶甲醇
BLEOMYCIN SULFATE, BPC
3-氨基-4-溴苯甲酸甲酯
[R,(R﹡,R﹡)]-2-(4-氟苯基 )-Β,Α-二羟基-5-(1-甲基乙基)-3-苯基-[(苯胺基)-羟基]-1H-吡咯-1-庚酸钙盐(无定型)
N-苄氧羰基-O-叔丁基-L-苏氨酸 二环己基铵盐
DL-NICOTINE, HYDROCHLORIDE, [PYRROLIDINE-2-14C]-
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