2-(三氟甲氧基)-5-氯苯胺 - Names and Identifiers
2-(三氟甲氧基)-5-氯苯胺 - Physico-chemical Properties
Molecular Formula | C7H5ClF3NO
|
Molar Mass | 211.57 |
Density | 1.468±0.06 g/cm3(Predicted) |
Boling Point | 214.5±35.0 °C(Predicted) |
Flash Point | 83.529°C |
Vapor Presure | 0.155mmHg at 25°C |
pKa | 1.39±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.4850 |
2-(三氟甲氧基)-5-氯苯胺 - Risk and Safety
2-(三氟甲氧基)-5-氯苯胺 - Introduction
5-chloro-2-(trifluoromethoxy)aniline, also known as 5-chloro-2-trifluoromethoxy aniline (5-chloro-2-(trifluoromethoxy)aniline), has the chemical formula C7H5ClF3NO.
Nature:
- 5-chloro-2-(trifluoromethoxy)aniline is a white to light yellow solid.
-has a high melting point and boiling point, is a strong aromatic amine compounds.
-Insoluble in water at room temperature, but soluble in many organic solvents, such as ethanol, dimethylformamide, etc.
Use:
- 5-chloro-2-(trifluoromethoxy)aniline is an important organic intermediate, which is widely used in the fields of medicine, pesticide and dye.
-In the field of medicine, it is used as an intermediate for the synthesis of some antibacterial agents and anti-tumor drugs.
-In the field of pesticides, it is used to make pesticides and herbicides.
-In the dye industry, it can be used as a precursor for the synthesis of organic dyes.
Method:
5-chloro-2-(trifluoromethoxy)aniline has many preparation methods, and the common methods include:
-The product is obtained by fluorination reaction of 2-amino-4-chlorophenol (2-amino-4-chlorophenol) and reaction with trifluoromethylformate (trifluoromethylmethoxide).
-The target product is obtained by the reduction reaction of 2-trifluoromethoxy-4-chloronitrobenzene (phenyl).
Safety Information:
5-chloro-2-(trifluoromethoxy)aniline should pay attention to the following safety matters during use and storage:
- 5-chloro-2-(trifluoromethoxy)aniline may cause irritation to the skin, eyes, respiratory tract, and digestive system, and may have adverse effects on the reproductive system.
-Wear appropriate personal protective equipment, such as goggles, gloves and masks.
-Avoid inhaling aerosols or dust, avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water and seek medical attention.
-storage should be stored in a dry, ventilated place, away from fire and combustibles.
Last Update:2024-04-09 19:05:49