2-(2-(2-Azidoethoxy)ethoxy)ethyl 4-methylbenzenesulfonate
2-(2-(2-azidoethoxy)ethoxy)ethyl 4-methylbenzenesulfonate
CAS: 178685-33-1
Molecular Formula: C13H19N3O5S
2-(2-(2-Azidoethoxy)ethoxy)ethyl 4-methylbenzenesulfonate - Names and Identifiers
2-(2-(2-Azidoethoxy)ethoxy)ethyl 4-methylbenzenesulfonate - Physico-chemical Properties
| Molecular Formula | C13H19N3O5S |
| Molar Mass | 329.37 |
| Appearance | Liquid |
| Storage Condition | 室温，干燥，密封 |
| In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
2-(2-(2-Azidoethoxy)ethoxy)ethyl 4-methylbenzenesulfonate - Reference Information
| biological activity | Azide-PEG3-Tos is a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules. Azide-PEG3-Tos is also a non-cleavable ADC linker containing 3 units of PEG and can be used to synthesize antibody-conjugated drugs (ADC). |
Last Update：2024-04-09 21:32:11
