2-(2-Hydroxyethoxy)-5-nitropyridine

2-(2-Hydroxyethoxy)-5-nitropyridine - Names and Identifiers

Name	2-(5-Nitro-2-pyridyloxy)ethanol
Synonyms	2-(5-Nitro-2-pyridyloxy)ethanol 2-(5-NITRO-2-PYRIDYLOXY)ETHANOL 2-(5-nitropyridin-2-yloxy)ethanol 2-(5-Nitropyridin-2-yloxy)ethanol 2-(2-Hydroxyethoxy)-5-nitropyridine 2-[(5-NITRO-2-PYRIDYL)OXY]ETHAN-1-OL 2-[(5-Nitro-2-pyridyl)oxy]ethan-1-ol 2-[(5-NITRO-2-PYRIDYL)THIO]ETHAN-1-OL 2-[(5-Nitro-2-pyridyl)thio]ethan-1-ol 2-[(5-Nitropyridin-2-yl)oxy]ethan-1-ol
CAS	143071-39-0
EINECS	640-278-6
InChI	InChI=1/C7H8N2O4/c10-3-4-13-7-2-1-6(5-8-7)9(11)12/h1-2,5,10H,3-4H2

2-(2-Hydroxyethoxy)-5-nitropyridine - Physico-chemical Properties

Molecular Formula	C7H8N2O4
Molar Mass	184.15
Density	1.39g/cm³
Melting Point	112-114°C
Boling Point	355.695°C at 760 mmHg
Flash Point	168.918°C
Vapor Presure	0mmHg at 25°C
BRN	150856
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.574
MDL	MFCD00052642

2-(2-Hydroxyethoxy)-5-nitropyridine - Risk and Safety

Safety Description

S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.

2-(2-Hydroxyethoxy)-5-nitropyridine - Introduction

2-(5-nitro-2-pyridyloxy) ethanol, also known as Nitrol or NPE, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: 2-(5-nitro-2-pyridyloxy) ethanol is a colorless to slightly yellow liquid.
-Solubility: It is soluble in water, alcohols and organic solvents.
-Melting point and boiling point: Its melting point is about 30°C, and its boiling point is about 220°C.

Use:
-Explosives: 2-(5-Nitro-2-pyridyloxy) ethanol is an important explosive ingredient and is often used in the preparation of explosives, rocket fuel and pyrotechnics.
-Pharmaceutical intermediate: It can also be used as an important pharmaceutical intermediate and is used to synthesize other compounds in the pharmaceutical field.

Preparation Method:
The preparation method of 2-(5-nitro-2-pyridyloxy) ethanol can be completed by the following steps:
1. Dissolve 2-pyridine ethanol in nitric acid.
2. The nitric acid solution was slowly added to the aqueous sodium hydroxide solution at low temperature.
3. Water bath heating was performed to raise the temperature of the solution in the reaction mixture.
4.2-(5-nitro-2-pyridyloxy) ethanol was obtained by distillation and crystallization.

Safety Information:
- 2-(5-nitro-2-pyridyloxy) ethanol is a harmful compound. Contact with or inhalation of its vapors can cause irritation and damage to the eyes, skin, and respiratory system. Therefore, wear appropriate protective equipment such as respirators, protective glasses and gloves during use.
-Avoid mixing the compound with combustibles for storage to avoid the risk of fire or explosion.
-When using or handling the compound, it should be operated in a well-ventilated place.
-Follow correct safe operating procedures when using, and properly dispose of waste in accordance with relevant laws and regulations.

Last Update：2024-04-09 20:48:19